Patient P-01605
Synthetic patientNBL-101 · Day 111 · 55–64 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Unstable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 46 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 57 GI-04 recommended — GI Support Protocol GI-04
- Day 58 Patient declined — Not now
- Day 70 ME-01 recommended — Monitoring Escalation ME-01
- Day 71 Patient accepted — Started ME-01 in the companion
- Day 74 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 46.
Primary contributors, last 14 days
- Treatment adherence-9
- Toxicity-3
What helped?
- GI Support Protocol GI-04Day 57Declined by patient
- Monitoring Escalation ME-01Day 70Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 84% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion59.9/100
worsening · +3.6 vs previous 14 d
Toxicity
Blood60.7/100
worsening · +3.7 vs previous 14 d
Sleep quality
Wearable15.6/100
improving · +2.3 vs previous 14 d
Energy level
Daily log1.5/10
worsening · -0.4 vs previous 14 d
Stress level
Daily log7.5/10
worsening · +0.5 vs previous 14 d
Steps
Wearable964
worsening · -115 vs previous 14 d
Adherence
Companion40.4 %
improving · +2.0 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading drifting · 19 from the failing basin, 69 from restoration.
Would help
- GI-04 GI Support Protocol73% improved among 123 similar · onset 8 d · confidence 96%
- NP-02 Dietary Support Protocol63% improved among 64 similar · onset 10 d · confidence 75%
- SC-12 Supportive Compound76% improved among 51 similar · onset 6 d · confidence 75%
- More fibreGI -3.2 next day on high-intake days · n 15
Would not help
- Keep fat lowGI +6.5 next day on high-intake days · n 25
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+6.5detractor · 95%
- Insoluble fibre-3.2supporter · 59%
- Spicy / capsaicin+2.2no signal · 40%
- Histamine load+1.4no signal · 21%
- Alcohol-0.5no signal · 15%
- Simple carbohydrates0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 31/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓65
- WearableResting HR 78 bpm
- Wearable964 steps/day
- WearableShort sleep window
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 60 and rising
- WearableSleep 4.8 h, below personal baseline
- Inflammatory signalling ↓40
- BloodInflammatory load index 63
- WearableHRV 36 ms, trending down
- Drug metabolism and exposure ↑20
- BloodToxicity index 61
DNA
Fictional pharmacogenomic panel
- CYP2D6 Intermediate metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.1 · butyrate capacity 31/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 35 ms
- Sleep
- 5.1 h
- Steps
- 1,192
- Resting HR
- 75 bpm
Daily log: GI score 60, nutritional resilience 34, adherence 40.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01751 | 59% | S14 | ME-01 | improved | 48 |
| P-01564 | 57% | S14 | ME-01 | improved | 39 |
| P-01732 | 56% | S14 | ME-01 | improved | 45 |
| P-01311 | 54% | S14 | ME-01 | improved | 49 |
| P-01728 | 54% | S14 | SC-12 | improved | 41 |
| P-01656 | 51% | S14 | ME-01 | improved | 41 |
| P-01834 | 50% | S14 | NP-02 | improved | 44 |
| P-01612 | 49% | S14 | ME-01 | improved | 51 |
| P-01720 | 49% | S14 | NP-02 | improved | 47 |
| P-01887 | 48% | S12 | ME-01 | improved | 43 |
| P-01482 | 47% | S14 | GI-04 | improved | 47 |
| P-01492 | 47% | S15 | ME-01 | improved | 44 |