Patient P-01635
Synthetic patientNBL-101 · Day 112 · 35–44 · M · baseline S02Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Deteriorating
GI state
Stable
Inflammatory state
Stable
Nutritional resilience
Declining
Discontinuation risk
56%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S02
- Day 46 SC-12 recommended — Supportive Compound SC-12
- Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 47 Patient accepted — Started SC-12 in the companion
- Day 53 GI symptom burden −13% vs expected — Supportive Compound SC-12
- Day 54 GI-04 recommended — GI Support Protocol GI-04
- Day 55 Patient accepted — Started GI-04 in the companion
- Day 59 Tolerance state changed — Unstable → Improving
- Day 63 GI symptom burden −28% vs expected — GI Support Protocol GI-04
- Day 69 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 47.
Primary contributors, last 14 days
- Toxicity+7
- Nutritional resilience-6
- Inflammatory activity-4
- GI instability+2
What helped?
- Supportive Compound SC-12Day 46Result: symptom burden −13%
- GI Support Protocol GI-04Day 54Result: symptom burden −28%
LIFE OS recommendation
Dietary Support Protocol NP-02
55%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion44.7/100
stable · -0.4 vs previous 14 d
Toxicity
Blood50.5/100
worsening · +2.4 vs previous 14 d
Sleep quality
Wearable16.7/100
stable · -0.2 vs previous 14 d
Energy level
Daily log3.2/10
worsening · -0.3 vs previous 14 d
Stress level
Daily log5.6/10
stable · +0.2 vs previous 14 d
Steps
Wearable1,379
worsening · -469 vs previous 14 d
Adherence
Companion50.2 %
worsening · -3.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 41 from the failing basin, 46 from restoration.
Would help
Would not help
- Keep spicy lowGI +2.7 next day on high-intake days · n 17
- Keep fat lowGI +2.6 next day on high-intake days · n 18
- Keep simple carbs lowGI +2.4 next day on high-intake days · n 15
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Spicy / capsaicin+2.7detractor · 70%
- Dietary fat load+2.6detractor · 73%
- Simple carbohydrates+2.4detractor · 72%
- Insoluble fibre+1.4no signal · 40%
- Histamine load+0.5no signal · 15%
- Alcohol-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 45
- WearableHRV 36 ms, trending down
- Autonomic recovery ↑65
- WearableResting HR 81 bpm
- Wearable1,379 steps/day
- WearableShort sleep window
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.3 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓20
- Daily logFibre intake low in recent food logs
- Drug metabolism and exposure ↑20
- BloodToxicity index 51
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Rapid metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.6 · butyrate capacity 47/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 32 ms
- Sleep
- 5.9 h
- Steps
- 1,546
- Resting HR
- 82 bpm
Daily log: GI score 45, nutritional resilience 43, adherence 50.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.