600 patients66,869 observations120 daysLIVE

Patient P-01654

Synthetic patientNBL-101 · Day 116 · 35–44 · M · baseline S08Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
4%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S08
  2. Day 63 CR-01 recommendedClinician Review CR-01
  3. Day 64 Patient acceptedStarted CR-01 in the companion
  4. Day 69 Deterioration detected before clinical escalationClinician Review CR-01

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • Toxicity-9
  • GI instability-5
  • Inflammatory activity-5
  • Nutritional resilience+2
  • Treatment adherence+2

What helped?

  • Clinician Review CR-01Day 63
    Result: deterioration detected before clinical escalation
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden
Companion
11.9/100
improving · -7.4 vs previous 14 d
Toxicity
Blood
6.5/100
improving · -6.7 vs previous 14 d
Sleep quality
Wearable
23.6/100
improving · +3.5 vs previous 14 d
Energy level
Daily log
7.4/10
improving · +0.6 vs previous 14 d
Stress level
Daily log
4.6/10
improving · -0.6 vs previous 14 d
Steps
Wearable
3,095
improving · +406 vs previous 14 d
Adherence
Companion
95.4 %
stable · -0.6 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →

Heading towards restoration · 98 from the failing basin, 11 from restoration.

Good elements to keep
  • Clinician Review CR-01
    intervention · steering +14.4
  • Butyrate producers intact
    hidden · steering +7.5
Main detractors to watch
  • FUT2 non-secretor
    hidden · steering -10.6
  • Low microbial diversity
    hidden · steering -7.7
  • Bacteroides fragilis elevated
    hidden · steering -7.4
  • Antibiotic course
    perturbation · steering -4.7
  • Simple carbohydrates
    detractor · GI +2.4 next day
  • Histamine load
    detractor · GI +2.3 next day
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Simple carbohydrates
    +2.4detractor · 95%
  • Histamine load
    +2.3detractor · 95%
  • Dietary fat load
    +1.1no signal · 33%
  • Spicy / capsaicin
    +1no signal · 35%
  • Insoluble fibre
    +0.6no signal · 18%
  • Alcohol
    -0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Autonomic recovery 65
    • WearableResting HR 74 bpm
    • Wearable3,095 steps/day
    • WearableShort sleep window
  • Mucosal barrier integrity 40
    • DNAFUT2 non-secretor lowers mucosal fucosylation
    • WearableSleep 5.6 h, below personal baseline
  • Inflammatory signalling 35
    • MicrobiomeBacteroides fragilis expansion
    • WearableHRV 34 ms, trending down
DNA
Fictional pharmacogenomic panel
  • FUT2 rs601338 AA (non-secretor)
    Reduced mucosal fucosylation
  • CYP2D6 Normal metabolizer
    Expected exposure
Microbiome
Shannon diversity 2.9 · butyrate capacity 70/100
  • Akkermansia muciniphilaNormal
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisHigh
  • Bifidobacterium longumLow
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
37 ms
Sleep
6.2 h
Steps
4,260
Resting HR
73 bpm
Daily log: GI score 12, nutritional resilience 65, adherence 95.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Keep fibre steady; no new sources this week
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Log the daily check-in; one line is enough
  • A 15-minute walk after lunch
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

PatientSimilarityBaselineInterventionOutcomeResponse today
P-0179657%S09SC-12improved86
P-0131256%S1288
P-0151253%S1781
P-0179853%S08NP-02improved78
P-0186953%S1484
P-0149552%S07BR-03improved85
P-0153652%S1381
P-0168352%S1384
P-0180652%S0877
P-0133151%S0179
P-0136651%S1087
P-0147251%S1375