Patient P-01663
Synthetic patientNBL-101 · Day 108 · 35–44 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Stable
Nutritional resilience
Declining
Discontinuation risk
66%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 No meaningful change — Dietary Support Protocol NP-02
- Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 51 SC-12 recommended — Supportive Compound SC-12
- Day 52 Patient accepted — Started SC-12 in the companion
- Day 58 GI-04 recommended — GI Support Protocol GI-04
- Day 58 GI symptom burden −17% vs expected — Supportive Compound SC-12
- Day 59 Patient accepted — Started GI-04 in the companion
- Day 64 Tolerance state changed — Unstable → Improving
- Day 67 GI symptom burden −30% vs expected — GI Support Protocol GI-04
- Day 73 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 47.
Primary contributors, last 14 days
- Nutritional resilience-11
- GI instability+9
- Toxicity+5
- Treatment adherence-3
What helped?
- Dietary Support Protocol NP-02Day 31Result: no meaningful change
- Supportive Compound SC-12Day 51Result: symptom burden −17%
- GI Support Protocol GI-04Day 58Result: symptom burden −30%
LIFE OS recommendation
Monitoring Escalation ME-01
82%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 3 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion38.7/100
improving · -9.1 vs previous 14 d
Toxicity
Blood40.5/100
worsening · +4.4 vs previous 14 d
Sleep quality
Wearable40.5/100
improving · +2.5 vs previous 14 d
Energy level
Daily log3.9/10
stable · +0.2 vs previous 14 d
Stress level
Daily log5.5/10
stable · -0.0 vs previous 14 d
Steps
Wearable6,920
improving · +396 vs previous 14 d
Adherence
Companion53.2 %
worsening · -5.0 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 46 from the failing basin, 41 from restoration.
Would help
Would not help
- NP-02 Dietary Support Protocolalready tried, no meaningful change
- Keep fat lowGI +6.7 next day on high-intake days · n 20
- Keep histamine lowGI +6.2 next day on high-intake days · n 24
- Keep fibre lowGI +6 next day on high-intake days · n 20
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+6.7detractor · 95%
- Histamine load+6.2detractor · 95%
- Insoluble fibre+6detractor · 95%
- Alcohol+1.1no signal · 22%
- Spicy / capsaicin-0.3no signal · 15%
- Simple carbohydrates-0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 42
- WearableHRV 23 ms, trending down
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 39/100
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓30
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Autonomic recovery ↓25
- WearableResting HR 85 bpm
- Drug metabolism and exposure ↑20
- BloodToxicity index 41
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 3 · butyrate capacity 39/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 28 ms
- Sleep
- 7.4 h
- Steps
- 7,873
- Resting HR
- 79 bpm
Daily log: GI score 39, nutritional resilience 46, adherence 53.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.