DeepGene damage signature
SyntheticSynthetic demo data2 samples: baseline day 0 · retest day 90
Damage score · retest day 90
32/100
vs baseline (day 0)
-14
6 improved · 0 worsened
synthetic signature · consistent with this patient's biology
- 3 opportunists above range: Escherichia coli, Klebsiella pneumoniae, Enterococcus faecium
- 2 keystone species absent
- 4 resistance genes
Pathogens / opportunists3/5
↓ from 5
Keystone species2/8
Diversity0/2
↓ from 1
Metabolic modules0/4
↓ from 1
Vitamin synthesis1/7
↓ from 2
Oral translocation1/1
Host DNA0/1
Tissue recycling0/1
Central mechanisms0/2
Virulence factors2/2
Antibiotic resistance genes4/4
↓ from 5
Genetic predisposition1/1
Opportunists above range
Escherichia coli 9.853% AR
Enterococcus faecium 4.926% AR
Klebsiella pneumoniae 2.956% AR
Keystone species absent
Akkermansia muciniphila, Bifidobacterium longum
Capacity
Shannon 3.15 · butyrate 791 CPM · SCFA 1201
1 vitamins below
Host & mechanisms
tissue recycling 32/100
oral translocation 2.27% AR
4 resistance genes · 2 virulence factors
Import a sample
A baseline sample re-initializes this patient's microbiome, pathways and predispositions from the measurement; a retest adds a comparison and updates them. Every theory, steering gain and dietary sensitivity downstream is then conditioned on the measured signature.
All elements · baseline → latest
Value, status vs the expected range, and the implication on health. Changes coloured: green improved / resolved, red worsened / new.
Pathogens / opportunists · 5
| Escherichia coli | 13.768 % AR · above range | 9.853 % AR · above range | expected <= 1% | In excess raises LPS load and zonulin release, opening tight junctions. |
| Klebsiella pneumoniae | 4.131 % AR · above range | 2.956 % AR · above range | expected <= 0.3% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Enterococcus faecium | 6.884 % AR · above range | 4.926 % AR · above range | expected <= 0.5% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Streptococcus gallolyticus | 1.377 % AR · above range | 0.054 % AR · in range(improved) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
| Clostridioides difficile | 1.377 % AR · above range | 0.053 % AR · in range(improved) | expected <= 0.1% | Opportunist above range; relevant after antibiotics and in inflammation. |
Keystone species · 8
| Akkermansia muciniphila | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Bifidobacterium longum | 0 % AR · absent | 0 % AR · absent | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Butyricicoccus pullicaecorum | 0.72 % AR · in range | 0.87 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Eubacterium rectale | 0.55 % AR · in range | 0.06 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Faecalibacterium prausnitzii | 0.59 % AR · in range | 1.29 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Lactobacillus species | 0.09 % AR · in range | 1.24 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Roseburia intestinalis | 1.19 % AR · in range | 1.21 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
| Ruminococcus bromii | 0.08 % AR · in range | 1.41 % AR · in range | expected 0.15-2.24% | Keystone butyrate producer / mucin specialist. |
Diversity · 2
| indice Shannon | 2.78 · below range | 3.15 · in range(improved) | expected >= 3.0 | Low diversity: fewer reserve metabolic routes, slower recovery after perturbation. |
| numar de specii detectate | 117 specii · in range | 141 specii · in range | expected >= 100 | Species count below reference. |
Metabolic modules · 4
| Butyrate production | 666 CPM · in range | 791 CPM · in range | expected 255.83-1089.91 CPM | Butyrate is the main colonocyte fuel and barrier signal. |
| Short Chain Fatty Acid Production | 1077 CPM · in range | 1201 CPM · in range | expected 535.03-1572.59 CPM | Total SCFA capacity. |
| GABA production | 393 CPM · in range | 407 CPM · in range | expected 87.31-766.53 CPM | Gut–brain axis capacity. |
| H2S production (sulfate reduction) | 328 CPM · above range | 98 CPM · in range(improved) | expected banda de referinta | Hydrogen sulfide above band irritates the mucosa. |
Vitamin synthesis · 7
| Vitamin B1 - Thiamin | 518 CPM · below range | 224 CPM · below range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B2 - Riboflavin | 303 CPM · below range | 3930 CPM · in range(improved) | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B5 - Pantothenic acid | 4270 CPM · in range | 4192 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B6 - Pyridoxine | 2863 CPM · in range | 4081 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B7 - Biotin | 3926 CPM · in range | 3086 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B9 - Folate | 2600 CPM · in range | 3068 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
| Vitamin B12 - Cobalamin | 2551 CPM · in range | 4051 CPM · in range | expected 2000-5000 CPM | Microbial synthesis capacity. |
Oral translocation · 1
| Translocare orala (indice) | 3.15 % AR · above range | 2.27 % AR · above range | expected <= 2% | Oral taxa in stool: reduced gastric barrier or dysbiosis. |
Host DNA · 1
| fragmentare mixta | 163 pb · in range | 162 pb · in range | expected 150-170 pb | Host cell-free DNA fragmentation pattern. |
Tissue recycling · 1
| indice de reciclare tisulara | 35 /100 · in range | 32 /100 · in range | expected < 35 | Epithelial turnover. |
Central mechanisms · 2
| molecular_mimicry | 60 /100 · in range | 58 /100 · in range | expected < 65 | Cross-reactive antigen load. |
| estrobolome | 64 /100 · in range | 56 /100 · in range | expected < 65 | Estrogen-recycling capacity. |
Virulence factors · 2
| fimD outer membrane usher | 84 potriviri/M · present | 76 potriviri/M · present | expected absent | Virulence factor detected. |
| chuA heme/hemoglobin receptor | 27 potriviri/M · present | 31 potriviri/M · present | expected absent | Virulence factor detected. |
Antibiotic resistance genes · 5
| sul1 | 6.6 citiri/M · present | 3.9 citiri/M · present | expected nedetectat | Resistance gene detected. |
| sul2 | 9.6 citiri/M · present | 2 citiri/M · present | expected nedetectat | Resistance gene detected. |
| tet(O/M/O) | 5.6 citiri/M · present | 7.2 citiri/M · present | expected nedetectat | Resistance gene detected. |
| Ecol_ampC_BLA | 4 citiri/M · present | 1.7 citiri/M · present | expected nedetectat | Resistance gene detected. |
| aadA | 9 citiri/M · present | resolved(resolved) | expected nedetectat | Resistance gene detected. |
Genetic predisposition · 1
| CYP2D6 | 2.7 OR · risk variant | 2.42 OR · risk variant | expected reference genotype | Expected exposure |