Patient P-01681
Synthetic patientNBL-101 · Day 114 · 55–64 · M · baseline S03Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Improving
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
11%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S03
- Day 13 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 13.
Primary contributors, last 14 days
- Toxicity-10
- Inflammatory activity-7
- Nutritional resilience+6
- Treatment adherence-4
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion16.4/100
improving · -5.7 vs previous 14 d
Toxicity
Blood12/100
improving · -3.7 vs previous 14 d
Sleep quality
Wearable61.3/100
stable · +2.1 vs previous 14 d
Energy level
Daily log6/10
stable · +0.2 vs previous 14 d
Stress level
Daily log3.3/10
improving · -0.3 vs previous 14 d
Steps
Wearable7,575
stable · +134 vs previous 14 d
Adherence
Companion88.5 %
improving · +4.4 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 69 from the failing basin, 48 from restoration.
Good elements to keep
- Butyrate producers intacthidden · steering +7.5
- Daily walks resumedperturbation · steering +3.3
Main detractors to watch
- Poor metabolizerhidden · steering -12.7
- Bacteroides fragilis elevatedhidden · steering -7.4
- Antibiotic courseperturbation · steering -4.7
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Simple carbohydrates+0.5no signal · 15%
- Insoluble fibre-0.5no signal · 15%
- Dietary fat load-0.4no signal · 15%
- Histamine load-0.2no signal · 15%
- Alcohol-0.1no signal · 15%
- Spicy / capsaicin-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↓25
- WearableResting HR 75 bpm
- Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 3 · butyrate capacity 52/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 54 ms
- Sleep
- 7.7 h
- Steps
- 6,544
- Resting HR
- 75 bpm
Daily log: GI score 16, nutritional resilience 68, adherence 89.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.