600 patients66,869 observations120 daysLIVE

Patient P-01687

Synthetic patientNBL-101 · Day 114 · 65–74 · F · baseline S12Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Favorable
Nutritional resilience
Declining
Discontinuation risk
19%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S12

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • Treatment adherence-9
  • GI instability+8
  • Nutritional resilience-5
  • Inflammatory activity+4
  • Toxicity-2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    8.2/100
    worsening · +0.8 vs previous 14 d
    Toxicity
    Blood
    19.3/100
    worsening · +6.0 vs previous 14 d
    Sleep quality
    Wearable
    40.1/100
    stable · -1.0 vs previous 14 d
    Energy level
    Daily log
    6.4/10
    stable · -0.2 vs previous 14 d
    Stress level
    Daily log
    2.7/10
    worsening · +0.4 vs previous 14 d
    Steps
    Wearable
    4,604
    stable · -193 vs previous 14 d
    Adherence
    Companion
    87.5 %
    stable · -2.0 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 105 from the failing basin, 19 from restoration.

    Good elements to keep
    • Butyrate producers intact
      hidden · steering +7.5
    • Daily walks resumed
      perturbation · steering +3.3
    Main detractors to watch
    • Bacteroides fragilis elevated
      hidden · steering -7.4
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Alcohol
      -0.8no signal · 18%
    • Insoluble fibre
      -0.6no signal · 15%
    • Dietary fat load
      -0.3no signal · 15%
    • Simple carbohydrates
      +0.3no signal · 15%
    • Histamine load
      -0.2no signal · 15%
    • Spicy / capsaicin
      0no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure 35
      • DNADPYD *2A → slower clearance
    • Inflammatory signalling 20
      • MicrobiomeBacteroides fragilis expansion
    • Autonomic recovery 20
      • WearableShort sleep window
    • Mucosal barrier integrity 10
      • WearableSleep 5.9 h, below personal baseline
    DNA
    Fictional pharmacogenomic panel
    • DPYD *2A heterozygous
      Slower drug clearance
    • CYP2D6 Normal metabolizer
      Expected exposure
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 3.5 · butyrate capacity 46/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    68 ms
    Sleep
    6.1 h
    Steps
    4,825
    Resting HR
    70 bpm
    Daily log: GI score 8, nutritional resilience 72, adherence 88.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0176337%S16ME-01improved100
    P-0130237%S11SC-12no change94
    P-0173045%S1793
    P-0172352%S1293
    P-0185738%S0492
    P-0132238%S0191
    P-0166240%S0291
    P-0152042%S0990
    P-0135443%S0390
    P-0176647%S05AD-05no change90
    P-0146443%S0690
    P-0184036%S0390