Patient P-01695
Therapy response
Unstable
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
15%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S01
- Day 28 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 28.
Primary contributors, last 14 days
- Toxicity-10
- GI instability-8
- Inflammatory activity-8
- Nutritional resilience+8
- Treatment adherence-6
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion18.7/100
improving · -3.2 vs previous 14 d
Toxicity
Blood12.9/100
improving · -1.3 vs previous 14 d
Sleep quality
Wearable34.6/100
improving · +2.3 vs previous 14 d
Energy level
Daily log4.8/10
stable · -0.0 vs previous 14 d
Stress level
Daily log4.6/10
stable · -0.1 vs previous 14 d
Steps
Wearable3,985
improving · +336 vs previous 14 d
Adherence
Companion82.5 %
worsening · -4.5 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 62 from the failing basin, 49 from restoration.
Good elements to keep
- Butyrate producers intacthidden · steering +7.5
- Daily walks resumedperturbation · steering +3.3
Main detractors to watch
- Poor metabolizerhidden · steering -12.7
- Dietary driftperturbation · steering -2.6
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Insoluble fibre+2no signal · 48%
- Alcohol-1.3no signal · 26%
- Dietary fat load+1.1no signal · 32%
- Histamine load-1no signal · 23%
- Simple carbohydrates+1no signal · 23%
- Spicy / capsaicin-0.7no signal · 17%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
- Autonomic recovery ↑40
- Wearable3,985 steps/day
- WearableShort sleep window
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Mucosal barrier integrity ↓10
- WearableSleep 6.0 h, below personal baseline
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.3 · butyrate capacity 48/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 44 ms
- Sleep
- 6.2 h
- Steps
- 3,719
- Resting HR
- 70 bpm
Daily log: GI score 19, nutritional resilience 64, adherence 83.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.