Patient P-01699
Synthetic patientNBL-101 · Day 112 · 55–64 · M · baseline S04Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Deteriorating
Inflammatory state
Stable
Nutritional resilience
Improving
Discontinuation risk
59%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S04
- Day 80 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 82 GI-04 recommended — GI Support Protocol GI-04
- Day 83 Patient accepted — Started GI-04 in the companion
- Day 91 GI symptom burden −24% vs expected — GI Support Protocol GI-04
- Day 97 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 80.
Primary contributors, last 14 days
- GI instability+10
- Toxicity-7
- Treatment adherence-6
- Nutritional resilience+4
What helped?
- GI Support Protocol GI-04Day 82Result: symptom burden −24%
LIFE OS recommendation
Dietary Support Protocol NP-02
66%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 86% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion52.6/100
stable · +1.2 vs previous 14 d
Toxicity
Blood47.8/100
worsening · +5.4 vs previous 14 d
Sleep quality
Wearable41.8/100
improving · +2.0 vs previous 14 d
Energy level
Daily log3.9/10
worsening · -0.3 vs previous 14 d
Stress level
Daily log6.2/10
worsening · +0.8 vs previous 14 d
Steps
Wearable8,557
stable · +23 vs previous 14 d
Adherence
Companion77.2 %
worsening · -11.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 50 from the failing basin, 46 from restoration.
Would help
Would not help
- Keep simple carbs lowGI +5 next day on high-intake days · n 15
- Keep fibre lowGI +3.4 next day on high-intake days · n 20
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Simple carbohydrates+5detractor · 95%
- Insoluble fibre+3.4detractor · 59%
- Spicy / capsaicin-1.2no signal · 16%
- Dietary fat load+0.9no signal · 15%
- Alcohol-0.6no signal · 15%
- Histamine load-0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 51
- Drug metabolism and exposure ↑55
- DNADPYD *2A → slower clearance
- BloodToxicity index 48
- Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 53 and rising
- Butyrate / short-chain fatty acid production ↓45
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑25
- WearableResting HR 85 bpm
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2 · butyrate capacity 47/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 38 ms
- Sleep
- 7.2 h
- Steps
- 7,503
- Resting HR
- 85 bpm
Daily log: GI score 53, nutritional resilience 43, adherence 77.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.