Patient P-01706
Therapy response
Improving
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Stable
Nutritional resilience
Stable
Discontinuation risk
60%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 48 SC-12 recommended — Supportive Compound SC-12
- Day 49 Patient accepted — Started SC-12 in the companion
- Day 55 GI symptom burden −20% vs expected — Supportive Compound SC-12
- Day 56 GI-04 recommended — GI Support Protocol GI-04
- Day 57 Patient accepted — Started GI-04 in the companion
- Day 61 Tolerance state changed — Unstable → Improving
- Day 65 GI symptom burden −24% vs expected — GI Support Protocol GI-04
- Day 71 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 47.
Primary contributors, last 14 days
- Toxicity+10
- GI instability-7
- Inflammatory activity-3
- Treatment adherence+2
What helped?
- Supportive Compound SC-12Day 48Result: symptom burden −20%
- GI Support Protocol GI-04Day 56Result: symptom burden −24%
LIFE OS recommendation
Dietary Support Protocol NP-02
55%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 66% showed improvement
- median effect visible after 10 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion47.3/100
improving · -3.7 vs previous 14 d
Toxicity
Blood38.6/100
stable · -1.4 vs previous 14 d
Sleep quality
Wearable34.1/100
improving · +3.4 vs previous 14 d
Energy level
Daily log3.8/10
improving · +0.3 vs previous 14 d
Stress level
Daily log6.6/10
stable · -0.1 vs previous 14 d
Steps
Wearable7,154
stable · -4 vs previous 14 d
Adherence
Companion52.1 %
worsening · -2.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 40 from the failing basin, 48 from restoration.
Would help
Would not help
- Keep fat lowGI +5.2 next day on high-intake days · n 21
- Keep histamine lowGI +5 next day on high-intake days · n 19
- Keep alcohol lowGI +4.2 next day on high-intake days · n 18
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+5.2detractor · 95%
- Histamine load+5detractor · 95%
- Alcohol+4.2detractor · 95%
- Simple carbohydrates+3.1detractor · 89%
- Spicy / capsaicin+2.6detractor · 66%
- Insoluble fibre+1.9no signal · 50%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 47 and rising
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 35/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 52
- WearableHRV 22 ms, trending down
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.6 · butyrate capacity 35/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 29 ms
- Sleep
- 6.9 h
- Steps
- 6,421
- Resting HR
- 64 bpm
Daily log: GI score 47, nutritional resilience 45, adherence 52.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01627 | 62% | S14 | GI-04 | improved | 54 |
| P-01624 | 58% | S14 | GI-04 | improved | 52 |
| P-01879 | 58% | S14 | SC-12 | improved | 51 |
| P-01543 | 53% | S14 | GI-04 | improved | 54 |
| P-01614 | 53% | S14 | GI-04 | improved | 53 |
| P-01336 | 52% | S03 | GI-04 | improved | 51 |
| P-01400 | 52% | S17 | GI-04 | improved | 51 |
| P-01573 | 50% | S14 | GI-04 | improved | 49 |
| P-01323 | 49% | S14 | GI-04 | improved | 50 |
| P-01365 | 49% | S14 | SC-12 | improved | 49 |
| P-01393 | 49% | S14 | GI-04 | improved | 53 |
| P-01438 | 49% | S14 | GI-04 | improved | 56 |