Patient P-01715
Synthetic patientNBL-101 · Day 111 · 35–44 · M · baseline S05Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
61%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S05
- Day 80 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 82 CR-01 recommended — Clinician Review CR-01
- Day 83 Patient declined — Not now
What changed?
Trajectory began diverging from predicted response on Day 80.
Primary contributors, last 14 days
- Treatment adherence-8
- GI instability-7
- Toxicity+6
- Inflammatory activity-2
What helped?
- Clinician Review CR-01Day 82Declined by patient
LIFE OS recommendation
GI Support Protocol GI-04
67%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion64.4/100
worsening · +3.1 vs previous 14 d
Toxicity
Blood52.6/100
worsening · +5.1 vs previous 14 d
Sleep quality
Wearable22.4/100
worsening · -2.9 vs previous 14 d
Energy level
Daily log1.7/10
worsening · -0.5 vs previous 14 d
Stress level
Daily log6.5/10
stable · +0.2 vs previous 14 d
Steps
Wearable4,805
worsening · -265 vs previous 14 d
Adherence
Companion63.8 %
worsening · -15.9 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 33 from the failing basin, 65 from restoration.
Would help
Would not help
- Keep histamine lowGI +4 next day on high-intake days · n 23
- Keep fat lowGI +3.6 next day on high-intake days · n 22
- Keep alcohol lowGI +3.5 next day on high-intake days · n 17
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+4detractor · 95%
- Dietary fat load+3.6detractor · 95%
- Alcohol+3.5detractor · 95%
- Simple carbohydrates+2.5detractor · 66%
- Spicy / capsaicin+1.5no signal · 36%
- Insoluble fibre-0.7no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 29/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 62
- WearableHRV 35 ms, trending down
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 64 and rising
- WearableSleep 5.7 h, below personal baseline
- Autonomic recovery ↓45
- WearableResting HR 80 bpm
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 53
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.4 · butyrate capacity 29/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 33 ms
- Sleep
- 5.5 h
- Steps
- 4,492
- Resting HR
- 82 bpm
Daily log: GI score 64, nutritional resilience 34, adherence 64.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.