Patient P-01720
Synthetic patientNBL-101 · Day 116 · 25–34 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Deteriorating
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 GI symptom burden −17% vs expected — Dietary Support Protocol NP-02
- Day 48 Tolerance state changed — Unstable → Improving
- Day 51 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 51.
Primary contributors, last 14 days
- Inflammatory activity+18
- GI instability+16
- Toxicity+13
- Treatment adherence+11
- Nutritional resilience-9
What helped?
- Dietary Support Protocol NP-02Day 31Result: symptom burden −17%
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion67.1/100
stable · +0.5 vs previous 14 d
Toxicity
Blood57.5/100
worsening · +4.3 vs previous 14 d
Sleep quality
Wearable16/100
worsening · -1.1 vs previous 14 d
Energy level
Daily log1.8/10
improving · +0.3 vs previous 14 d
Stress level
Daily log6.6/10
stable · +0.2 vs previous 14 d
Steps
Wearable1,426
worsening · -549 vs previous 14 d
Adherence
Companion51.3 %
worsening · -2.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 23 from the failing basin, 74 from restoration.
Would help
- GI-04 GI Support Protocol73% improved among 124 similar · onset 8 d · confidence 97%
- ME-01 Monitoring Escalation100% improved among 77 similar · onset 3 d · confidence 79%
- SC-12 Supportive Compound76% improved among 51 similar · onset 6 d · confidence 79%
- More alcoholGI -6.3 next day on high-intake days · n 18
Would not help
- Keep fat lowGI +5.9 next day on high-intake days · n 22
- Keep simple carbs lowGI +5 next day on high-intake days · n 23
- Keep spicy lowGI +3.6 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Alcohol-6.3supporter · 95%
- Dietary fat load+5.9detractor · 95%
- Simple carbohydrates+5detractor · 95%
- Spicy / capsaicin+3.6detractor · 67%
- Histamine load-2.6no signal · 49%
- Insoluble fibre+2.6no signal · 52%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 25/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 68
- WearableHRV 36 ms, trending down
- Autonomic recovery ↓65
- WearableResting HR 78 bpm
- Wearable1,426 steps/day
- WearableShort sleep window
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 67 and rising
- WearableSleep 5.1 h, below personal baseline
- Drug metabolism and exposure ↑20
- BloodToxicity index 58
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.3 · butyrate capacity 25/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 40 ms
- Sleep
- 5.5 h
- Steps
- 1,862
- Resting HR
- 77 bpm
Daily log: GI score 67, nutritional resilience 34, adherence 51.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.