Patient P-01721
Synthetic patientNBL-101 · Day 117 · 35–44 · F · baseline S14Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S14
- Day 47 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 47.
Primary contributors, last 14 days
- Toxicity-10
- Nutritional resilience+6
- Inflammatory activity-4
- GI instability-2
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
92%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion73.5/100
stable · -1.3 vs previous 14 d
Toxicity
Blood48.5/100
improving · -12.7 vs previous 14 d
Sleep quality
Wearable31.7/100
improving · +3.4 vs previous 14 d
Energy level
Daily log1.9/10
improving · +0.8 vs previous 14 d
Stress level
Daily log7.5/10
improving · -0.4 vs previous 14 d
Steps
Wearable1,993
stable · -12 vs previous 14 d
Adherence
Companion46.1 %
stable · +0.9 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 16 from the failing basin, 82 from restoration.
Would help
- GI-04 GI Support Protocol73% improved among 124 similar · onset 8 d · confidence 97%
- ME-01 Monitoring Escalation100% improved among 78 similar · onset 3 d · confidence 80%
- NP-02 Dietary Support Protocol63% improved among 64 similar · onset 10 d · confidence 80%
- More fibreGI -2.5 next day on high-intake days · n 17
Would not help
- Keep fat lowGI +4.7 next day on high-intake days · n 22
- Keep histamine lowGI +3.7 next day on high-intake days · n 16
- Keep alcohol lowGI +2.5 next day on high-intake days · n 22
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.7detractor · 95%
- Histamine load+3.7detractor · 95%
- Insoluble fibre-2.5supporter · 62%
- Alcohol+2.5detractor · 65%
- Simple carbohydrates+1.7no signal · 39%
- Spicy / capsaicin-1.1no signal · 33%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 74 and rising
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 49
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 41/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓45
- WearableResting HR 75 bpm
- Wearable1,993 steps/day
- Inflammatory signalling ↓25
- BloodInflammatory load index 66
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 2.8 · butyrate capacity 41/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 49 ms
- Sleep
- 6.8 h
- Steps
- 524
- Resting HR
- 77 bpm
Daily log: GI score 74, nutritional resilience 30, adherence 46.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01897 | 56% | S14 | ME-01 | improved | 43 |
| P-01736 | 48% | S03 | ME-01 | improved | 46 |
| P-01564 | 46% | S14 | ME-01 | improved | 39 |
| P-01612 | 46% | S14 | ME-01 | improved | 51 |
| P-01728 | 46% | S14 | SC-12 | improved | 41 |
| P-01531 | 45% | S14 | ME-01 | improved | 51 |
| P-01605 | 45% | S14 | ME-01 | improved | 41 |
| P-01656 | 45% | S14 | ME-01 | improved | 41 |
| P-01751 | 45% | S14 | ME-01 | improved | 48 |
| P-01615 | 43% | S14 | ME-01 | improved | 48 |
| P-01492 | 42% | S15 | ME-01 | improved | 44 |
| P-01517 | 42% | S06 | NP-02 | improved | 27 |