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Patient P-01722

Synthetic patientNBL-101 · Day 113 · 55–64 · M · baseline S09Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Favorable
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Declining
Discontinuation risk
14%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S09
  2. Day 78 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 78.

Primary contributors, last 14 days
  • GI instability-7
  • Nutritional resilience-6
  • Inflammatory activity-5
  • Toxicity+4
  • Treatment adherence-3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    11.6/100
    improving · -2.7 vs previous 14 d
    Toxicity
    Blood
    20/100
    improving · -3.0 vs previous 14 d
    Sleep quality
    Wearable
    52.5/100
    stable · -0.5 vs previous 14 d
    Energy level
    Daily log
    6/10
    improving · +0.5 vs previous 14 d
    Stress level
    Daily log
    3.9/10
    improving · -0.2 vs previous 14 d
    Steps
    Wearable
    8,288
    stable · -79 vs previous 14 d
    Adherence
    Companion
    80.4 %
    worsening · -8.2 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 74 from the failing basin, 43 from restoration.

    Good elements to keep
    • Butyrate producers intact
      hidden · steering +7.5
    Main detractors to watch
    • Poor metabolizer
      hidden · steering -12.7
    • IL6 high-expression variant
      hidden · steering -7.3
    • Spicy / capsaicin
      perturbation · steering -3.9
    • Poor-sleep week
      perturbation · steering -3
    • Spicy / capsaicin
      detractor · GI +2 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Spicy / capsaicin
      +2detractor · 77%
    • Histamine load
      -1.1no signal · 36%
    • Insoluble fibre
      +0.6no signal · 20%
    • Alcohol
      -0.4no signal · 15%
    • Simple carbohydrates
      +0.3no signal · 15%
    • Dietary fat load
      +0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Inflammatory signalling ↓25
      • DNAIL6 -174 variant raises baseline inflammatory tone
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    Microbiome
    Shannon diversity 4 · butyrate capacity 81/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    39 ms
    Sleep
    7.5 h
    Steps
    7,938
    Resting HR
    68 bpm
    Daily log: GI score 12, nutritional resilience 64, adherence 80.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0131345%S01BR-03improved32
    P-0132040%S09HY-01improved38
    P-0134637%S12DT-01improved52
    P-0161836%S10GI-04improved39
    P-0173135%S01ME-01improved32
    P-0134234%S11DT-01improved48
    P-0159334%S10HY-01improved56
    P-0175234%S20DT-01improved50
    P-0177334%S05AD-05improved27
    P-0186134%S12HY-01improved47
    P-0137433%S08HY-01improved49
    P-0138533%S06HY-01improved50