600 patients66,869 observations120 daysLIVE
← Patients

Patient P-01740

Synthetic patientNBL-101 · Day 111 · 45–54 · M · baseline S06Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
21%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 started — Baseline state S06

What changed?

Trajectory is tracking the baseline prediction.

Primary contributors, last 14 days
  • GI instability-12
  • Nutritional resilience+9
  • Treatment adherence-7
  • Inflammatory activity-6
  • Toxicity+6

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    20.4/100
    improving · -10.8 vs previous 14 d
    Toxicity
    Blood
    31.9/100
    worsening · +7.3 vs previous 14 d
    Sleep quality
    Wearable
    63.1/100
    improving · +5.8 vs previous 14 d
    Energy level
    Daily log
    6.1/10
    improving · +0.3 vs previous 14 d
    Stress level
    Daily log
    3.7/10
    improving · -0.4 vs previous 14 d
    Steps
    Wearable
    9,639
    improving · +487 vs previous 14 d
    Adherence
    Companion
    88.1 %
    worsening · -6.4 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 65 from the failing basin, 28 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • Keep histamine low
      GI +3.3 next day on high-intake days · n 18
    • Keep spicy low
      GI +3.2 next day on high-intake days · n 24
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +3.3detractor · 95%
    • Spicy / capsaicin
      +3.2detractor · 95%
    • Insoluble fibre
      -2.1no signal · 44%
    • Alcohol
      +0.6no signal · 17%
    • Simple carbohydrates
      -0.4no signal · 15%
    • Dietary fat load
      +0.1no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓60
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Drug metabolism and exposure ↑40
      • DNACYP2D6 poor metabolizer → higher exposure
    • Inflammatory signalling ↓25
      • DNAIL6 -174 variant raises baseline inflammatory tone
    • Butyrate / short-chain fatty acid production ↓25
      • MicrobiomeF. prausnitzii depleted
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Poor metabolizer
      Higher exposure at standard dose
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 3.7 · butyrate capacity 64/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiLow
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    46 ms
    Sleep
    7.7 h
    Steps
    8,909
    Resting HR
    60 bpm
    Daily log: GI score 20, nutritional resilience 63, adherence 88.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0155828%S09——86
    P-0172627%S12——86
    P-0133426%S17——85
    P-0142027%S03——85
    P-0141126%S18——84
    P-0168327%S13——84
    P-0166528%S06——83
    P-0139926%S01——83
    P-0132426%S02——83
    P-0144826%S10——83
    P-0153026%S16——83
    P-0143527%S03——82