Patient P-01744

Synthetic patientNBL-101 · Day 108 · 45–54 · M · baseline S18Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Favorable

GI state

Deteriorating

Inflammatory state

Favorable

Nutritional resilience

Declining

Discontinuation risk

32%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S18
Day 27 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 27.

Primary contributors, last 14 days

GI instability+8
Nutritional resilience-5
Treatment adherence+4

What helped?

No interventions yet.

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

29.5/100

worsening · +5.1 vs previous 14 d

Toxicity

Blood

16.4/100

worsening · +3.0 vs previous 14 d

Sleep quality

Wearable

45.4/100

stable · -1.5 vs previous 14 d

Energy level

Daily log

5.5/10

stable · -0.2 vs previous 14 d

Stress level

Daily log

3.8/10

worsening · +0.2 vs previous 14 d

Steps

Wearable

2,469

stable · -94 vs previous 14 d

Adherence

Companion

83.5 %

improving · +4.1 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 58 from the failing basin, 51 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.

Would not help

Nothing clearly counter-productive in the record.

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Histamine load
+1.6no signal · 29%
Simple carbohydrates
-1.5no signal · 31%
Spicy / capsaicin
-0.9no signal · 18%
Alcohol
+0.8no signal · 16%
Dietary fat load
-0.5no signal · 15%
Insoluble fibre
-0.4no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Autonomic recovery ↑45
- WearableResting HR 76 bpm
- Wearable2,469 steps/day
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted

DNA

Fictional pharmacogenomic panel

CYP2D6 Intermediate metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 3.9 · butyrate capacity 75/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 53 ms
Sleep: 7.2 h
Steps: 3,392
Resting HR: 75 bpm

Daily log: GI score 30, nutritional resilience 56, adherence 84.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01731	46%	S01	ME-01	improved	32
P-01773	43%	S05	AD-05	improved	27
P-01313	36%	S01	BR-03	improved	32
P-01618	33%	S10	GI-04	improved	39
P-01320	32%	S09	HY-01	improved	38
P-01374	31%	S08	HY-01	improved	49
P-01752	31%	S20	DT-01	improved	50
P-01342	30%	S11	DT-01	improved	48
P-01405	30%	S14	SC-12	improved	44
P-01861	30%	S12	HY-01	improved	47
P-01346	29%	S12	DT-01	improved	52
P-01432	29%	S14	GI-04	improved	46