Patient P-01749
Synthetic patientNBL-101 · Day 103 · 65–74 · F · baseline S04Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
15%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S04
- Day 16 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 16.
Primary contributors, last 14 days
- GI instability-8
- Inflammatory activity-6
- Treatment adherence+5
- Toxicity+5
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion17/100
worsening · +6.6 vs previous 14 d
Toxicity
Blood25.6/100
worsening · +5.7 vs previous 14 d
Sleep quality
Wearable58.9/100
worsening · -5.2 vs previous 14 d
Energy level
Daily log6.4/10
worsening · -1.0 vs previous 14 d
Stress level
Daily log4.3/10
worsening · +0.3 vs previous 14 d
Steps
Wearable8,432
worsening · -616 vs previous 14 d
Adherence
Companion93.5 %
stable · +1.5 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 78 from the failing basin, 13 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
Would not help
- HY-01 Hydration Protocolonly 40% improved among 10 similar
- Keep spicy lowGI +2.1 next day on high-intake days · n 24
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Spicy / capsaicin+2.1detractor · 67%
- Alcohol+1.4no signal · 41%
- Histamine load-0.7no signal · 22%
- Dietary fat load+0.6no signal · 16%
- Simple carbohydrates+0.3no signal · 15%
- Insoluble fibre0no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
- Inflammatory signalling ↓25
- DNAIL6 -174 variant raises baseline inflammatory tone
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Rapid metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 4.4 · butyrate capacity 66/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 43 ms
- Sleep
- 7.5 h
- Steps
- 8,083
- Resting HR
- 67 bpm
Daily log: GI score 17, nutritional resilience 65, adherence 94.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.