Patient P-01756
Synthetic patientNBL-101 · Day 108 · 45–54 · F · baseline S03Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Favorable
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
10%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S03
- Day 28 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 28.
Primary contributors, last 14 days
- Inflammatory activity-8
- GI instability-4
- Treatment adherence+4
- Nutritional resilience-2
- Toxicity-2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion12.2/100
worsening · +1.9 vs previous 14 d
Toxicity
Blood18.7/100
improving · -10.3 vs previous 14 d
Sleep quality
Wearable66.2/100
stable · +0.8 vs previous 14 d
Energy level
Daily log7.3/10
improving · +0.5 vs previous 14 d
Stress level
Daily log3.4/10
improving · -0.4 vs previous 14 d
Steps
Wearable4,340
improving · +246 vs previous 14 d
Adherence
Companion92.6 %
stable · +1.8 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 83 from the failing basin, 17 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
Would not help
- Nothing clearly counter-productive in the record.
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+1.9no signal · 38%
- Histamine load+1.8no signal · 40%
- Spicy / capsaicin-1no signal · 21%
- Alcohol+0.9no signal · 19%
- Simple carbohydrates-0.5no signal · 15%
- Insoluble fibre+0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
DNA
Fictional pharmacogenomic panel
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 3.6 · butyrate capacity 79/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 47 ms
- Sleep
- 7.5 h
- Steps
- 3,622
- Resting HR
- 61 bpm
Daily log: GI score 12, nutritional resilience 70, adherence 93.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.