Patient P-01768
Synthetic patientNBL-101 · Day 100 · 35–44 · M · baseline S20Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Stable
Inflammatory state
Deteriorating
Nutritional resilience
Stable
Discontinuation risk
53%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S20
- Day 75 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 75.
Primary contributors, last 14 days
- Treatment adherence-24
- Toxicity+17
- Inflammatory activity+5
- Nutritional resilience+4
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
64%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 86% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion50/100
worsening · +8.0 vs previous 14 d
Toxicity
Blood55.8/100
worsening · +21.9 vs previous 14 d
Sleep quality
Wearable16.9/100
worsening · -7.0 vs previous 14 d
Energy level
Daily log2.7/10
worsening · -1.3 vs previous 14 d
Stress level
Daily log6.5/10
worsening · +0.7 vs previous 14 d
Steps
Wearable6,881
worsening · -513 vs previous 14 d
Adherence
Companion66.3 %
worsening · -13.9 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 36 from the failing basin, 53 from restoration.
Would help
Would not help
- Keep fat lowGI +5 next day on high-intake days · n 19
- Keep histamine lowGI +4.3 next day on high-intake days · n 23
- Keep simple carbs lowGI +4.1 next day on high-intake days · n 18
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+5detractor · 95%
- Histamine load+4.3detractor · 95%
- Simple carbohydrates+4.1detractor · 95%
- Insoluble fibre-2no signal · 43%
- Alcohol+1.5no signal · 34%
- Spicy / capsaicin+0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↑85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 56
- WearableHRV 25 ms, trending down
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 50 and rising
- WearableSleep 5.8 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 42/100
- Daily logFibre intake low in recent food logs
- Drug metabolism and exposure ↑20
- BloodToxicity index 56
- Autonomic recovery ↑20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.6 · butyrate capacity 42/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 25 ms
- Sleep
- 5.5 h
- Steps
- 7,578
- Resting HR
- 69 bpm
Daily log: GI score 50, nutritional resilience 45, adherence 66.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.