600 patients66,869 observations120 daysLIVE

Patient P-01769

Synthetic patientNBL-101 · Day 112 · 25–34 · F · baseline S20Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
52%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S20
  2. Day 76 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 76.

Primary contributors, last 14 days
  • Nutritional resilience+15
  • GI instability-12
  • Toxicity-10
  • Treatment adherence-7
  • Inflammatory activity-6

What helped?

No interventions yet.

    LIFE OS recommendation
    GI Support Protocol GI-04
    55%
    probability of meaningful tolerance improvement
    • 284 similar trajectories
    • 85% showed improvement
    • median effect visible after 8 days

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    52.1/100
    stable · -1.3 vs previous 14 d
    Toxicity
    Blood
    50.8/100
    worsening · +11.5 vs previous 14 d
    Sleep quality
    Wearable
    42/100
    improving · +3.2 vs previous 14 d
    Energy level
    Daily log
    3/10
    stable · +0.0 vs previous 14 d
    Stress level
    Daily log
    6.3/10
    worsening · +0.3 vs previous 14 d
    Steps
    Wearable
    1,712
    improving · +212 vs previous 14 d
    Adherence
    Companion
    66.3 %
    worsening · -9.6 vs previous 14 d
    This trajectory is doing well — what to keep, what to watch
    Steering view →

    Heading towards restoration · 42 from the failing basin, 50 from restoration.

    Good elements to keep
    • Daily walks resumed
      perturbation · steering +3.3
    Main detractors to watch
    • Low butyrate capacity
      hidden · steering -17.5
    • Low microbial diversity
      hidden · steering -7.7
    • Enterobacteriaceae elevated
      hidden · steering -7.4
    • Simple carbohydrates
      perturbation · steering -4
    • Simple carbohydrates
      detractor · GI +2.5 next day
    • Dietary fat load
      detractor · GI +2 next day
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Simple carbohydrates
      +2.5detractor · 77%
    • Dietary fat load
      +2detractor · 76%
    • Alcohol
      +1.6detractor · 57%
    • Histamine load
      -0.6no signal · 17%
    • Spicy / capsaicin
      -0.4no signal · 15%
    • Insoluble fibre
      0no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Butyrate / short-chain fatty acid production 55
      • MicrobiomeButyrate capacity 23/100
      • Daily logFibre intake low in recent food logs
    • Autonomic recovery 40
      • Wearable1,712 steps/day
      • WearableShort sleep window
    • Inflammatory signalling 25
      • BloodInflammatory load index 54
    • Mucosal barrier integrity 20
      • Daily logGI symptom score 52 and rising
    • Drug metabolism and exposure 20
      • BloodToxicity index 51
    DNA
    Fictional pharmacogenomic panel
    • CYP2D6 Intermediate metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 2.6 · butyrate capacity 23/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisNormal
    • Bifidobacterium longumLow
    • EnterobacteriaceaeHigh
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    52 ms
    Sleep
    7.1 h
    Steps
    1,577
    Resting HR
    71 bpm
    Daily log: GI score 52, nutritional resilience 42, adherence 66.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
    • Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
    • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Track each bowel movement today: time, stool form, urgency, overnight waking
    • A 15-minute walk after lunch
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • Electrolyte solution, one sachet after any loose stool
    • Fictional demo item: oral nutrition supplement with lunch

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0135323%S0775
    P-0189624%S0775
    P-0160425%S0171
    P-0138624%S1370
    P-0135226%S2070
    P-0175026%S1669
    P-0169947%S04GI-04improved69
    P-0150824%S1868
    P-0175426%S1468
    P-0150927%S1768
    P-0187524%S1167
    P-0181725%S1467