Patient P-01802
Synthetic patientNBL-101 · Day 116 · 35–44 · F · baseline S20Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S20
- Day 31 NP-02 recommended — Dietary Support Protocol NP-02
- Day 32 Patient accepted — Started NP-02 in the companion
- Day 42 GI symptom burden −14% vs expected — Dietary Support Protocol NP-02
- Day 48 Tolerance state changed — Unstable → Improving
- Day 50 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 50.
Primary contributors, last 14 days
- GI instability+10
- Toxicity-6
- Inflammatory activity+4
- Treatment adherence-4
What helped?
- Dietary Support Protocol NP-02Day 31Result: symptom burden −14%
LIFE OS recommendation
GI Support Protocol GI-04
84%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion61.1/100
worsening · +6.0 vs previous 14 d
Toxicity
Blood49.2/100
worsening · +3.3 vs previous 14 d
Sleep quality
Wearable16.1/100
worsening · -2.8 vs previous 14 d
Energy level
Daily log3/10
worsening · -0.3 vs previous 14 d
Stress level
Daily log7.5/10
worsening · +0.5 vs previous 14 d
Steps
Wearable4,419
stable · -66 vs previous 14 d
Adherence
Companion38.2 %
worsening · -4.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 20 from the failing basin, 69 from restoration.
Would help
Would not help
- Keep fat lowGI +3.4 next day on high-intake days · n 27
- Keep histamine lowGI +2.9 next day on high-intake days · n 24
- Keep alcohol lowGI +2 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+3.4detractor · 95%
- Histamine load+2.9detractor · 95%
- Alcohol+2detractor · 75%
- Insoluble fibre-1.2no signal · 37%
- Simple carbohydrates-0.5no signal · 15%
- Spicy / capsaicin-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓90
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 61 and rising
- WearableSleep 5.9 h, below personal baseline
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 43/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 62
- WearableHRV 22 ms, trending down
- Autonomic recovery ↑45
- WearableResting HR 76 bpm
- WearableShort sleep window
- Drug metabolism and exposure ↑20
- BloodToxicity index 49
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3 · butyrate capacity 43/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 16 ms
- Sleep
- 5.7 h
- Steps
- 4,051
- Resting HR
- 75 bpm
Daily log: GI score 61, nutritional resilience 41, adherence 38.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01692 | 51% | S14 | NP-02 | improved | 49 |
| P-01810 | 50% | S05 | NP-02 | improved | 43 |
| P-01402 | 49% | S04 | GI-04 | improved | 37 |
| P-01462 | 48% | S14 | NP-02 | improved | 47 |
| P-01482 | 48% | S14 | GI-04 | improved | 47 |
| P-01332 | 47% | S14 | NP-02 | improved | 43 |
| P-01496 | 47% | S14 | SC-12 | improved | 46 |
| P-01872 | 47% | S14 | NP-02 | improved | 47 |
| P-01406 | 46% | S18 | GI-04 | improved | 50 |
| P-01409 | 46% | S14 | SC-12 | improved | 41 |
| P-01429 | 46% | S09 | GI-04 | improved | 45 |
| P-01447 | 46% | S15 | GI-04 | improved | 44 |