600 patients66,869 observations120 daysLIVE

Patient P-01813

Synthetic patientNBL-101 · Day 119 · 35–44 · M · baseline S01Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
96%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S01
  2. Day 31 NP-02 recommendedDietary Support Protocol NP-02
  3. Day 32 Patient acceptedStarted NP-02 in the companion
  4. Day 42 No meaningful changeDietary Support Protocol NP-02
  5. Day 49 Trajectory diverged from predictionObserved response fell below the model's expected path.
  6. Day 66 ME-01 recommendedMonitoring Escalation ME-01
  7. Day 67 Patient acceptedStarted ME-01 in the companion
  8. Day 70 Deterioration detected before clinical escalationMonitoring Escalation ME-01

What changed?

Trajectory began diverging from predicted response on Day 49.

Primary contributors, last 14 days
  • GI instability+20
  • Inflammatory activity+14
  • Nutritional resilience-7
  • Toxicity-7

What helped?

  • Dietary Support Protocol NP-02Day 31
    Result: no meaningful change
  • Monitoring Escalation ME-01Day 66
    Result: deterioration detected before clinical escalation
LIFE OS recommendation
GI Support Protocol GI-04
91%
probability of meaningful tolerance improvement
  • 284 similar trajectories
  • 83% showed improvement
  • median effect visible after 8 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden
Companion
67.7/100
worsening · +8.9 vs previous 14 d
Toxicity
Blood
46.4/100
improving · -4.4 vs previous 14 d
Sleep quality
Wearable
35.5/100
worsening · -3.4 vs previous 14 d
Energy level
Daily log
2.6/10
worsening · -0.3 vs previous 14 d
Stress level
Daily log
8.3/10
stable · +0.3 vs previous 14 d
Steps
Wearable
300
worsening · -452 vs previous 14 d
Adherence
Companion
45.5 %
stable · -1.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards failing · 18 from the failing basin, 74 from restoration.

Would help
  • GI-04 GI Support Protocol
    73% improved among 124 similar · onset 8 d · confidence 95%
  • SC-12 Supportive Compound
    76% improved among 51 similar · onset 6 d · confidence 76%
  • CR-01 Clinician Review
    100% improved among 8 similar · onset 5 d · confidence 76%
Would not help
  • NP-02 Dietary Support Protocol
    already tried, no meaningful change
  • Keep fat low
    GI +5.9 next day on high-intake days · n 20
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Dietary fat load
    +5.9detractor · 95%
  • Insoluble fibre
    -1.6no signal · 28%
  • Spicy / capsaicin
    +1.2no signal · 19%
  • Histamine load
    -0.7no signal · 15%
  • Simple carbohydrates
    +0.7no signal · 15%
  • Alcohol
    +0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Butyrate / short-chain fatty acid production 80
    • MicrobiomeButyrate capacity 40/100
    • MicrobiomeF. prausnitzii depleted
    • Daily logFibre intake low in recent food logs
  • Autonomic recovery 45
    • WearableResting HR 74 bpm
    • Wearable300 steps/day
  • Inflammatory signalling 40
    • BloodInflammatory load index 61
    • WearableHRV 24 ms, trending down
  • Mucosal barrier integrity 20
    • Daily logGI symptom score 68 and rising
  • Drug metabolism and exposure 20
    • BloodToxicity index 46
DNA
Fictional pharmacogenomic panel
  • CYP2D6 Normal metabolizer
    Expected exposure
Microbiome
Shannon diversity 3.1 · butyrate capacity 40/100
  • Akkermansia muciniphilaNormal
  • Faecalibacterium prausnitziiLow
  • Bacteroides fragilisNormal
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
25 ms
Sleep
6.6 h
Steps
784
Resting HR
74 bpm
Daily log: GI score 68, nutritional resilience 36, adherence 46.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
  • Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
  • Track each bowel movement today: time, stool form, urgency, overnight waking
  • A 15-minute walk after lunch
  • Keep the sleep window steady
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the scheduled dose as agreed with your care team
  • Electrolyte solution, one sachet after any loose stool
  • Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

PatientSimilarityBaselineInterventionOutcomeResponse today
P-0138618%S1370
P-0135218%S2070
P-0169923%S04GI-04improved69
P-0150818%S1868
P-0150919%S1768
P-0187725%S01CR-01improved67
P-0162919%S1966
P-0171422%S14GI-04improved66
P-0185828%S14NP-02improved65
P-0131719%S1965
P-0164319%S1765
P-0141731%S14GI-04improved65