Patient P-01826
Synthetic patientNBL-101 · Day 103 · 65–74 · F · baseline S10Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Stable
GI state
Unstable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
92%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 NBL-101 started — Baseline state S10
- Day 46 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 46.
Primary contributors, last 14 days
- Treatment adherence-5
- Nutritional resilience+3
- Toxicity+3
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
88%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
GI burden
Companion69/100
worsening · +8.5 vs previous 14 d
Toxicity
Blood56.8/100
worsening · +7.1 vs previous 14 d
Sleep quality
Wearable33.8/100
stable · -0.6 vs previous 14 d
Energy level
Daily log2.1/10
worsening · -0.6 vs previous 14 d
Stress level
Daily log6.9/10
worsening · +0.4 vs previous 14 d
Steps
Wearable5,885
worsening · -393 vs previous 14 d
Adherence
Companion38 %
worsening · -9.0 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 20 from the failing basin, 74 from restoration.
Would help
Would not help
- Keep fat lowGI +6.4 next day on high-intake days · n 21
- Keep simple carbs lowGI +5.6 next day on high-intake days · n 19
- Keep histamine lowGI +5.1 next day on high-intake days · n 23
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+6.4detractor · 95%
- Simple carbohydrates+5.6detractor · 95%
- Histamine load+5.1detractor · 95%
- Insoluble fibre+3.8detractor · 95%
- Alcohol+3.8detractor · 85%
- Spicy / capsaicin+2.3no signal · 54%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 42/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓50
- DNAFUT2 non-secretor lowers mucosal fucosylation
- Daily logGI symptom score 69 and rising
- Inflammatory signalling ↓40
- BloodInflammatory load index 62
- WearableHRV 28 ms, trending down
- Autonomic recovery ↑25
- WearableResting HR 81 bpm
- Drug metabolism and exposure ↑20
- BloodToxicity index 57
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.6 · butyrate capacity 42/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 25 ms
- Sleep
- 6.7 h
- Steps
- 5,559
- Resting HR
- 82 bpm
Daily log: GI score 69, nutritional resilience 34, adherence 38.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-01762 | 50% | S14 | NP-02 | no change | 40 |
| P-01463 | 49% | S14 | NP-02 | no change | 41 |
| P-01492 | 49% | S15 | ME-01 | improved | 44 |
| P-01760 | 49% | S14 | — | — | 42 |
| P-01751 | 48% | S14 | ME-01 | improved | 48 |
| P-01407 | 47% | S14 | NP-02 | no change | 44 |
| P-01582 | 47% | S14 | GI-04 | no change | 45 |
| P-01605 | 47% | S14 | ME-01 | improved | 41 |
| P-01690 | 47% | S14 | — | — | 46 |
| P-01799 | 47% | S19 | NP-02 | no change | 51 |
| P-01868 | 47% | S14 | — | — | 47 |
| P-01897 | 47% | S14 | ME-01 | improved | 43 |