600 patients66,869 observations120 daysLIVE

Patient P-01836

Synthetic patientNBL-101 · Day 116 · 35–44 · F · baseline S10Steering view · 3DOpen companion preview
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
10%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S10
  2. Day 25 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 25.

Primary contributors, last 14 days
  • GI instability-30
  • Inflammatory activity-13
  • Nutritional resilience+13
  • Toxicity+12
  • Treatment adherence-2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    3/100
    improving · -11.0 vs previous 14 d
    Toxicity
    Blood
    24.5/100
    improving · -1.4 vs previous 14 d
    Sleep quality
    Wearable
    32.9/100
    improving · +4.0 vs previous 14 d
    Energy level
    Daily log
    6.2/10
    improving · +0.7 vs previous 14 d
    Stress level
    Daily log
    4/10
    improving · -0.7 vs previous 14 d
    Steps
    Wearable
    7,172
    improving · +535 vs previous 14 d
    Adherence
    Companion
    83.1 %
    stable · -1.3 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards restoration · 84 from the failing basin, 52 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • Nothing clearly counter-productive in the record.
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Dietary fat load
      -3.8no signal · 48%
    • Spicy / capsaicin
      +3.7no signal · 52%
    • Alcohol
      -0.9no signal · 15%
    • Histamine load
      -0.5no signal · 15%
    • Simple carbohydrates
      +0.5no signal · 15%
    • Insoluble fibre
      -0.3no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Inflammatory signalling 45
      • DNAIL6 -174 variant raises baseline inflammatory tone
      • MicrobiomeBacteroides fragilis expansion
    • Autonomic recovery 20
      • WearableShort sleep window
    • Mucosal barrier integrity 10
      • WearableSleep 5.9 h, below personal baseline
    DNA
    Fictional pharmacogenomic panel
    • IL6 -174 G/C
      Higher inflammatory tone
    • CYP2D6 Normal metabolizer
      Expected exposure
    • MTHFR C677T
      Reduced folate turnover
    Microbiome
    Shannon diversity 4.1 · butyrate capacity 77/100
    • Akkermansia muciniphilaNormal
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    39 ms
    Sleep
    6.0 h
    Steps
    6,965
    Resting HR
    60 bpm
    Daily log: GI score 3, nutritional resilience 71, adherence 83.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0153020%S1683
    P-0138420%S0882
    P-0146020%S1282
    P-0177020%S1382
    P-0147720%S1980
    P-0166420%S0380
    P-0142220%S1680
    P-0147120%S1979
    P-0130620%S0279
    P-0155320%S0279
    P-0143920%S18ME-01improved79
    P-0148920%S0278