Patient P-01851

Synthetic patientNBL-101 · Day 104 · 65–74 · F · baseline S16Steering view · 3D Open companion preview

Therapy response

Declining

Tolerance

Improving

GI state

Deteriorating

Inflammatory state

Deteriorating

Nutritional resilience

Stable

Discontinuation risk

35%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 NBL-101 started — Baseline state S16
Day 49 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 49.

Primary contributors, last 14 days

GI instability+7
Inflammatory activity+6
Nutritional resilience-4
Toxicity-4

What helped?

No interventions yet.

LIFE OS recommendation

Hydration Protocol HY-01

36%

probability of meaningful tolerance improvement

284 similar trajectories
40% showed improvement
median effect visible after 4 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

GI burden

Companion

38.7/100

worsening · +3.5 vs previous 14 d

Toxicity

Blood

25.2/100

improving · -4.8 vs previous 14 d

Sleep quality

Wearable

16.3/100

stable · +0.1 vs previous 14 d

Energy level

Daily log

3.8/10

worsening · -0.3 vs previous 14 d

Stress level

Daily log

5.1/10

stable · -0.0 vs previous 14 d

Steps

Wearable

1,580

improving · +150 vs previous 14 d

Adherence

Companion

93.2 %

stable · -0.2 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 49 from the failing basin, 38 from restoration.

Would help

DT-01 Dosing / Timing Recommendation
67% improved among 6 similar · onset 5 d · confidence 59%

Would not help

HY-01 Hydration Protocol
only 40% improved among 10 similar

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Spicy / capsaicin
-2.8no signal · 40%
Insoluble fibre
+2.4no signal · 47%
Simple carbohydrates
-1.6no signal · 26%
Dietary fat load
+1.5no signal · 23%
Histamine load
+0.7no signal · 15%
Alcohol
+0.6no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.4 h, below personal baseline
Autonomic recovery ↓40
- Wearable1,580 steps/day
- WearableShort sleep window
Inflammatory signalling ↑35
- MicrobiomeBacteroides fragilis expansion
- WearableHRV 21 ms, trending down

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 4.1 · butyrate capacity 55/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 30 ms
Sleep: 6.0 h
Steps: 2,600
Resting HR: 62 bpm

Daily log: GI score 39, nutritional resilience 53, adherence 93.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
A 15-minute walk after lunch
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-01804	42%	S19	AD-05	improved	61
P-01430	40%	S05	CR-01	improved	54
P-01571	36%	S13	SC-12	improved	57
P-01342	33%	S11	DT-01	improved	48
P-01346	31%	S12	DT-01	improved	52
P-01574	31%	S14	GI-04	improved	47
P-01593	31%	S10	HY-01	improved	56
P-01752	31%	S20	DT-01	improved	50
P-01321	30%	S12	GI-04	improved	53
P-01323	30%	S14	GI-04	improved	50
P-01325	30%	S16	GI-04	improved	54
P-01383	30%	S14	NP-02	improved	40