600 patients66,869 observations120 daysLIVE

Patient P-01883

Synthetic patientNBL-101 · Day 108 · 65–74 · M · baseline S16Steering view · 3DOpen companion preview
Therapy response
Favorable
Tolerance
Deteriorating
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
17%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 NBL-101 startedBaseline state S16
  2. Day 17 Trajectory diverged from predictionObserved response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 17.

Primary contributors, last 14 days
  • Treatment adherence+4
  • Toxicity+4
  • GI instability+3
  • Inflammatory activity-2
  • Nutritional resilience+2

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    GI burden
    Companion
    20.7/100
    improving · -4.0 vs previous 14 d
    Toxicity
    Blood
    19.4/100
    worsening · +8.5 vs previous 14 d
    Sleep quality
    Wearable
    67.4/100
    stable · +1.4 vs previous 14 d
    Energy level
    Daily log
    6.2/10
    worsening · -0.3 vs previous 14 d
    Stress level
    Daily log
    4.2/10
    worsening · +0.3 vs previous 14 d
    Steps
    Wearable
    2,723
    improving · +191 vs previous 14 d
    Adherence
    Companion
    93.9 %
    stable · +1.5 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 85 from the failing basin, 3 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    Would not help
    • Nothing clearly counter-productive in the record.
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Alcohol
      +0.9no signal · 26%
    • Simple carbohydrates
      -0.4no signal · 15%
    • Insoluble fibre
      -0.2no signal · 15%
    • Dietary fat load
      -0.1no signal · 15%
    • Spicy / capsaicin
      -0.1no signal · 15%
    • Histamine load
      0no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Drug metabolism and exposure 35
      • DNADPYD *2A → slower clearance
    • Mucosal barrier integrity 30
      • MicrobiomeAkkermansia low → thinner mucus layer
    • Inflammatory signalling 20
      • MicrobiomeBacteroides fragilis expansion
    • Autonomic recovery 20
      • Wearable2,723 steps/day
    DNA
    Fictional pharmacogenomic panel
    • DPYD *2A heterozygous
      Slower drug clearance
    • CYP2D6 Rapid metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 3.9 · butyrate capacity 70/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumNormal
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    66 ms
    Sleep
    7.8 h
    Steps
    3,289
    Resting HR
    65 bpm
    Daily log: GI score 21, nutritional resilience 64, adherence 94.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Avoid known triggers for now: fried or oily food, dairy, alcohol
    What to do
    • Log the daily check-in; one line is enough
    • A 15-minute walk after lunch
    • Keep the sleep window steady
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the scheduled dose as agreed with your care team
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0176638%S05AD-05no change90
    P-0180430%S19AD-05improved61
    P-0154128%S09AD-05no change43
    P-0167748%S05BR-03no change86
    P-0132942%S08BR-03improved79
    P-0149534%S07BR-03improved85
    P-0168929%S13BR-03no change50
    P-0165435%S08CR-01improved85
    P-0143028%S05CR-01improved54
    P-0147944%S15DT-01improved84
    P-0185542%S04DT-01improved73
    P-0172435%S10DT-01improved63