Patient P-03070
Therapy response
Stable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Stable
Nutritional resilience
Unstable
Discontinuation risk
73%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S14
- Day 60 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 61 GI-04 recommended — GI Support Protocol GI-04
- Day 62 Patient accepted — Started GI-04 in the companion
- Day 70 GI symptom burden −29% vs expected — GI Support Protocol GI-04
- Day 76 Tolerance state changed — Unstable → Improving
- Day 80 ME-01 recommended — Monitoring Escalation ME-01
- Day 81 Patient accepted — Started ME-01 in the companion
- Day 84 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 60.
Primary contributors, last 14 days
- GI instability+8
- Nutritional resilience-7
- Treatment adherence+4
- Inflammatory activity+3
- Toxicity-2
What helped?
- GI Support Protocol GI-04Day 61Result: symptom burden −29%
- Monitoring Escalation ME-01Day 80Result: deterioration detected before clinical escalation
LIFE OS recommendation
Dosing / Timing Recommendation DT-01
72%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 83% showed improvement
- median effect visible after 5 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log3.9/10
worsening · -0.3 vs previous 14 d
Stress level
Daily log5/10
worsening · +0.4 vs previous 14 d
Pessimism score
Daily log5.2/10
worsening · +0.2 vs previous 14 d
Sleep quality
Wearable29.5/100
worsening · -6.5 vs previous 14 d
Libido
Daily log4.1/10
worsening · -0.2 vs previous 14 d
HRV
Wearable52.8 ms
stable · -1.6 vs previous 14 d
Toxicity
Blood35.4/100
improving · -3.6 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 35 from the failing basin, 54 from restoration.
Would help
- DT-01 Dosing / Timing Recommendation83% improved among 12 similar · onset 5 d · confidence 72%
- NP-02 Dietary Support Protocol57% improved among 14 similar · onset 10 d · confidence 72%
- CR-01 Clinician Review100% improved among 5 similar · onset 5 d · confidence 72%
- More proteinGI -4.2 next day on high-intake days · n 19
Would not help
- AD-05 Adherence Supportonly 18% improved among 11 similar
- Keep fat lowGI +4.1 next day on high-intake days · n 24
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-4.2supporter · 95%
- Dietary fat load+4.1detractor · 95%
- Lactose+0.7no signal · 18%
- Histamine load-0.6no signal · 15%
- Alcohol-0.6no signal · 16%
- Caffeine+0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 30/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 51
- Autonomic recovery ↓40
- Wearable3,925 steps/day
- WearableShort sleep window
- Mucosal barrier integrity ↓30
- Daily logGI symptom score 55 and rising
- WearableSleep 5.8 h, below personal baseline
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2 · butyrate capacity 30/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 55 ms
- Sleep
- 5.3 h
- Steps
- 4,817
- Resting HR
- 65 bpm
Daily log: GI score 55, nutritional resilience 42, adherence 50.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.