Patient P-03081
Therapy response
Improving
Tolerance
Deteriorating
GI state
Stable
Inflammatory state
Stable
Nutritional resilience
Unstable
Discontinuation risk
58%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S10
- Day 55 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 71 GI-04 recommended — GI Support Protocol GI-04
- Day 72 Patient accepted — Started GI-04 in the companion
- Day 80 GI symptom burden −21% vs expected — GI Support Protocol GI-04
- Day 86 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 55.
Primary contributors, last 14 days
- Nutritional resilience-5
- Treatment adherence+5
- Toxicity+5
- GI instability-2
- Inflammatory activity-2
What helped?
- GI Support Protocol GI-04Day 71Result: symptom burden −21%
LIFE OS recommendation
Supportive Compound SC-12
73%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 88% showed improvement
- median effect visible after 6 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log3.4/10
improving · +0.2 vs previous 14 d
Stress level
Daily log7.2/10
improving · -0.4 vs previous 14 d
Pessimism score
Daily log5.7/10
stable · -0.1 vs previous 14 d
Sleep quality
Wearable26.7/100
worsening · -1.7 vs previous 14 d
Libido
Daily log2.2/10
worsening · -0.2 vs previous 14 d
HRV
Wearable16.9 ms
stable · -0.3 vs previous 14 d
Toxicity
Blood53.6/100
worsening · +3.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 38 from the failing basin, 51 from restoration.
Would help
- ME-01 Monitoring Escalation100% improved among 11 similar · onset 3 d · confidence 70%
- SC-12 Supportive Compound89% improved among 9 similar · onset 6 d · confidence 70%
- NP-02 Dietary Support Protocol57% improved among 14 similar · onset 10 d · confidence 70%
- More proteinGI -3.5 next day on high-intake days · n 21
Would not help
- AD-05 Adherence Supportonly 20% improved among 10 similar
- Keep fat lowGI +3.8 next day on high-intake days · n 20
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+3.8detractor · 95%
- Protein-3.5supporter · 95%
- Caffeine-0.7no signal · 21%
- Histamine load-0.3no signal · 15%
- Alcohol+0.3no signal · 15%
- Lactose-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 27/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓65
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 50
- WearableHRV 17 ms, trending down
- Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 53 and rising
- Drug metabolism and exposure ↑20
- BloodToxicity index 54
- Autonomic recovery ↑20
- Wearable2,307 steps/day
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 1.8 · butyrate capacity 27/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 18 ms
- Sleep
- 6.7 h
- Steps
- 2,098
- Resting HR
- 65 bpm
Daily log: GI score 53, nutritional resilience 40, adherence 53.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.