Patient P-03090
Therapy response
Stable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Stable
Nutritional resilience
Declining
Discontinuation risk
68%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S02
- Day 62 GI-04 recommended — GI Support Protocol GI-04
- Day 63 Patient accepted — Started GI-04 in the companion
- Day 71 GI symptom burden −40% vs expected — GI Support Protocol GI-04
- Day 75 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 75 ME-01 recommended — Monitoring Escalation ME-01
- Day 76 Patient accepted — Started ME-01 in the companion
- Day 77 Tolerance state changed — Unstable → Improving
- Day 79 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 75.
Primary contributors, last 14 days
- Nutritional resilience-15
- GI instability+12
- Treatment adherence+8
What helped?
- GI Support Protocol GI-04Day 62Result: symptom burden −40%
- Monitoring Escalation ME-01Day 75Result: deterioration detected before clinical escalation
LIFE OS recommendation
Dosing / Timing Recommendation DT-01
60%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 73% showed improvement
- median effect visible after 5 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log4.5/10
stable · +0.1 vs previous 14 d
Stress level
Daily log5.6/10
stable · -0.1 vs previous 14 d
Pessimism score
Daily log5.7/10
stable · -0.1 vs previous 14 d
Sleep quality
Wearable46.2/100
worsening · -4.8 vs previous 14 d
Libido
Daily log3.9/10
stable · -0.1 vs previous 14 d
HRV
Wearable39.6 ms
worsening · -2.2 vs previous 14 d
Toxicity
Blood37.8/100
improving · -2.7 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 36 from the failing basin, 52 from restoration.
Would help
- DT-01 Dosing / Timing Recommendation73% improved among 11 similar · onset 5 d · confidence 66%
- NP-02 Dietary Support Protocol57% improved among 14 similar · onset 10 d · confidence 66%
- CR-01 Clinician Review100% improved among 5 similar · onset 5 d · confidence 66%
- More proteinGI -4 next day on high-intake days · n 18
Would not help
- AD-05 Adherence Supportonly 30% improved among 10 similar
- Keep fat lowGI +4.6 next day on high-intake days · n 22
- Keep histamine lowGI +4.6 next day on high-intake days · n 26
- Keep lactose lowGI +3.3 next day on high-intake days · n 14
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+4.6detractor · 95%
- Histamine load+4.6detractor · 95%
- Protein-4supporter · 95%
- Lactose+3.3detractor · 77%
- Caffeine+2no signal · 37%
- Alcohol+0.6no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 53 and rising
- Inflammatory signalling ↑70
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 47
- Butyrate / short-chain fatty acid production ↓55
- MicrobiomeButyrate capacity 28/100
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↓20
- Wearable3,504 steps/day
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Rapid metabolizerExpected exposure
Microbiome
Shannon diversity 3 · butyrate capacity 28/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 46 ms
- Sleep
- 6.8 h
- Steps
- 3,732
- Resting HR
- 69 bpm
Daily log: GI score 53, nutritional resilience 43, adherence 50.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.