Patient P-03117
Therapy response
Unstable
Tolerance
Favorable
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
18%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S05
- Day 107 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 107.
Primary contributors, last 14 days
- GI instability-14
- Nutritional resilience+12
- Treatment adherence-8
- Inflammatory activity-5
- Toxicity+2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.9 h, below personal baseline
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
- Autonomic recovery ↑20
- WearableShort sleep window
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 3.3 · butyrate capacity 48/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 63 ms
- Sleep
- 6.0 h
- Steps
- 9,245
- Resting HR
- 59 bpm
Daily log: GI score 15, nutritional resilience 67, adherence 82.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-03497 | 51% | S05 | — | — | 29 |
| P-03153 | 47% | S12 | BR-03 | no change | 40 |
| P-03441 | 46% | S19 | AD-05 | improved | 37 |
| P-03455 | 46% | S08 | — | — | 32 |
| P-03034 | 45% | S14 | AD-05 | no change | 30 |
| P-03122 | 44% | S13 | AD-05 | no change | 40 |
| P-03274 | 44% | S08 | — | — | 40 |
| P-03308 | 44% | S04 | BR-03 | improved | 39 |
| P-03362 | 44% | S20 | — | — | 42 |
| P-03369 | 44% | S18 | AD-05 | no change | 37 |
| P-03149 | 43% | S20 | — | — | 37 |
| P-03351 | 43% | S07 | AD-05 | no change | 51 |