Patient P-03139
Therapy response
Improving
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
14%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S13
- Day 102 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 102.
Primary contributors, last 14 days
- Inflammatory activity-10
- GI instability-9
- Toxicity+7
- Nutritional resilience+4
- Treatment adherence+2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients.
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Autonomic recovery ↓45
- WearableResting HR 73 bpm
- WearableShort sleep window
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Inflammatory signalling ↓20
- MicrobiomeBacteroides fragilis expansion
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 3.6 · butyrate capacity 53/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 54 ms
- Sleep
- 6.6 h
- Steps
- 9,396
- Resting HR
- 74 bpm
Daily log: GI score 19, nutritional resilience 64, adherence 86.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-03197 | 53% | S14 | — | — | 41 |
| P-03274 | 53% | S08 | — | — | 40 |
| P-03122 | 52% | S13 | AD-05 | no change | 40 |
| P-03149 | 52% | S20 | — | — | 37 |
| P-03202 | 52% | S14 | — | — | 44 |
| P-03014 | 51% | S01 | — | — | 32 |
| P-03250 | 50% | S12 | — | — | 44 |
| P-03277 | 49% | S14 | BR-03 | improved | 41 |
| P-03369 | 49% | S18 | AD-05 | no change | 37 |
| P-03497 | 49% | S05 | — | — | 29 |
| P-03498 | 49% | S08 | — | — | 31 |
| P-03424 | 48% | S12 | AD-05 | improved | 41 |