Patient P-03424

Synthetic patientONX-7 · Day 146 · 25–34 · M · baseline S12Steering view · 3D Open companion preview

Therapy response

Unstable

Tolerance

Improving

GI state

Improving

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

14%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 ONX-7 started — Baseline state S12
Day 76 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 90 AD-05 recommended — Adherence Support AD-05
Day 91 Patient accepted — Started AD-05 in the companion
Day 96 GI symptom burden −15% vs expected — Adherence Support AD-05
Day 102 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 76.

Primary contributors, last 14 days

Toxicity-15
Nutritional resilience+12
GI instability-4
Treatment adherence-4

What helped?

Adherence Support AD-05Day 90
Result: symptom burden −15%

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Energy level

Daily log

6.8/10

improving · +0.4 vs previous 14 d

Stress level

Daily log

3.8/10

improving · -0.6 vs previous 14 d

Pessimism score

Daily log

4.3/10

improving · -0.2 vs previous 14 d

Sleep quality

Wearable

67.2/100

stable · +0.5 vs previous 14 d

Libido

Daily log

5.7/10

improving · +0.3 vs previous 14 d

HRV

Wearable

42.5 ms

stable · +1.2 vs previous 14 d

Toxicity

Blood

12/100

improving · -3.9 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 67 from the failing basin, 37 from restoration.

Good elements to keep

Adherence Support AD-05
intervention · steering +24.7
Protein (supports)
perturbation · steering +12.1
Butyrate producers intact
hidden · steering +7.5
Daily walks resumed
perturbation · steering +3.3
Protein
supporter · GI -5.9 next day

Main detractors to watch

Low microbial diversity
hidden · steering -7.7
Poor-sleep week
perturbation · steering -3
Dietary drift
perturbation · steering -2.6

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-5.9supporter · 95%
Caffeine
-2.7no signal · 42%
Histamine load
+1.8no signal · 29%
Dietary fat load
-0.8no signal · 15%
Alcohol
-0.7no signal · 15%
Lactose
+0.7no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 2.8 · butyrate capacity 56/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiNormal
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 45 ms
Sleep: 7.9 h
Steps: 5,349
Resting HR: 63 bpm

Daily log: GI score 18, nutritional resilience 65, adherence 82.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Keep fibre steady; no new sources this week
Avoid known triggers for now: fried or oily food, dairy, alcohol

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the scheduled dose as agreed with your care team
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-03197	51%	S14	—	—	41
P-03250	49%	S12	—	—	44
P-03380	49%	S16	AD-05	improved	34
P-03139	48%	S13	—	—	42
P-03418	47%	S11	—	—	38
P-03277	46%	S14	BR-03	improved	41
P-03014	45%	S01	—	—	32
P-03202	45%	S14	—	—	44
P-03173	44%	S17	—	—	39
P-03455	44%	S08	—	—	32
P-03111	43%	S07	AD-05	no change	48
P-03129	43%	S18	AD-05	no change	32