Patient P-03146
Therapy response
Improving
Tolerance
Deteriorating
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
58%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S14
- Day 39 NP-02 recommended — Dietary Support Protocol NP-02
- Day 40 Patient accepted — Started NP-02 in the companion
- Day 50 GI symptom burden −23% vs expected — Dietary Support Protocol NP-02
- Day 56 Tolerance state changed — Unstable → Improving
- Day 60 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 69 GI-04 recommended — GI Support Protocol GI-04
- Day 70 Patient accepted — Started GI-04 in the companion
- Day 74 ME-01 recommended — Monitoring Escalation ME-01
- Day 75 Patient accepted — Started ME-01 in the companion
- Day 78 GI symptom burden −24% vs expected — GI Support Protocol GI-04
- Day 78 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
- Day 84 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 60.
Primary contributors, last 14 days
- GI instability-18
- Toxicity+8
- Nutritional resilience+7
- Inflammatory activity-5
- Treatment adherence-4
What helped?
- Dietary Support Protocol NP-02Day 39Result: symptom burden −23%
- GI Support Protocol GI-04Day 69Result: symptom burden −24%
- Monitoring Escalation ME-01Day 74Result: deterioration detected before clinical escalation
LIFE OS recommendation
Dosing / Timing Recommendation DT-01
67%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 82% showed improvement
- median effect visible after 5 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log4.3/10
worsening · -0.2 vs previous 14 d
Stress level
Daily log6/10
worsening · +0.5 vs previous 14 d
Pessimism score
Daily log4.8/10
worsening · +0.3 vs previous 14 d
Sleep quality
Wearable44.5/100
worsening · -3.6 vs previous 14 d
Libido
Daily log3.1/10
stable · -0.1 vs previous 14 d
HRV
Wearable54.5 ms
worsening · -2.4 vs previous 14 d
Toxicity
Blood34.7/100
stable · -0.9 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 41 from the failing basin, 47 from restoration.
Would help
Would not help
- AD-05 Adherence Supportonly 27% improved among 11 similar
- Keep fat lowGI +4.6 next day on high-intake days · n 23
- Keep alcohol lowGI +3.9 next day on high-intake days · n 18
- Keep lactose lowGI +3.5 next day on high-intake days · n 18
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-5.2supporter · 95%
- Dietary fat load+4.6detractor · 95%
- Alcohol+3.9detractor · 95%
- Lactose+3.5detractor · 95%
- Histamine load-1.9no signal · 43%
- Caffeine-0.5no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 31/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↓45
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 49
- Mucosal barrier integrity ↓20
- Daily logGI symptom score 47 and rising
- Autonomic recovery ↑20
- Wearable3,661 steps/day
DNA
Fictional pharmacogenomic panel
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.6 · butyrate capacity 31/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 54 ms
- Sleep
- 6.2 h
- Steps
- 3,132
- Resting HR
- 70 bpm
Daily log: GI score 47, nutritional resilience 42, adherence 55.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.