Patient P-03164
Therapy response
Stable
Tolerance
Unstable
GI state
Stable
Inflammatory state
Unstable
Nutritional resilience
Unstable
Discontinuation risk
62%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S11
- Day 102 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 102.
Primary contributors, last 14 days
- Toxicity+19
- Nutritional resilience-5
- Inflammatory activity+4
- Treatment adherence-3
What helped?
No interventions yet.
LIFE OS recommendation
GI Support Protocol GI-04
58%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 82% showed improvement
- median effect visible after 8 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log3.3/10
stable · -0.0 vs previous 14 d
Stress level
Daily log7.2/10
stable · +0.0 vs previous 14 d
Pessimism score
Daily log5.6/10
stable · -0.1 vs previous 14 d
Sleep quality
Wearable51.8/100
improving · +5.4 vs previous 14 d
Libido
Daily log1.5/10
worsening · -0.2 vs previous 14 d
HRV
Wearable46.6 ms
stable · +0.8 vs previous 14 d
Toxicity
Blood64.9/100
worsening · +5.9 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 36 from the failing basin, 60 from restoration.
Would help
- GI-04 GI Support Protocol73% improved among 33 similar · onset 8 d · confidence 56%
- ME-01 Monitoring Escalation100% improved among 11 similar · onset 3 d · confidence 64%
- SC-12 Supportive Compound89% improved among 9 similar · onset 6 d · confidence 64%
- More proteinGI -2.1 next day on high-intake days · n 14
Would not help
- AD-05 Adherence Supportonly 20% improved among 10 similar
- Keep histamine lowGI +2.4 next day on high-intake days · n 23
- Keep lactose lowGI +1.8 next day on high-intake days · n 22
- Keep alcohol lowGI +1.5 next day on high-intake days · n 19
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Histamine load+2.4detractor · 95%
- Protein-2.1supporter · 81%
- Lactose+1.8detractor · 74%
- Alcohol+1.5detractor · 67%
- Dietary fat load+1.2no signal · 49%
- Caffeine+0.8no signal · 34%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 57 and rising
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 43/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Inflammatory signalling ↑45
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 63
- Autonomic recovery ↓25
- WearableResting HR 74 bpm
- Drug metabolism and exposure ↑20
- BloodToxicity index 65
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 1.9 · butyrate capacity 43/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 45 ms
- Sleep
- 7.3 h
- Steps
- 5,600
- Resting HR
- 74 bpm
Daily log: GI score 57, nutritional resilience 32, adherence 63.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.