Patient P-03205
Therapy response
Unstable
Tolerance
Favorable
GI state
Favorable
Inflammatory state
Favorable
Nutritional resilience
Favorable
Discontinuation risk
16%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S09
- Day 24 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 24.
Primary contributors, last 14 days
- Treatment adherence+10
- GI instability+2
- Inflammatory activity+2
- Nutritional resilience+2
- Toxicity-2
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log5.5/10
stable · +0.2 vs previous 14 d
Stress level
Daily log4.1/10
improving · -0.2 vs previous 14 d
Pessimism score
Daily log4.6/10
stable · -0.2 vs previous 14 d
Sleep quality
Wearable26.5/100
stable · +0.8 vs previous 14 d
Libido
Daily log5/10
improving · +0.3 vs previous 14 d
HRV
Wearable39.7 ms
stable · +0.3 vs previous 14 d
Toxicity
Blood17/100
improving · -6.1 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 69 from the failing basin, 38 from restoration.
Good elements to keep
- Butyrate producers intacthidden · steering +7.5
- Protein (supports)perturbation · steering +4.7
- Proteinsupporter · GI -2.8 next day
Main detractors to watch
- Poor metabolizerhidden · steering -12.7
- Caffeineperturbation · steering -8.1
- Bacteroides fragilis elevatedhidden · steering -7.4
- Poor-sleep weekperturbation · steering -3
- Caffeinedetractor · GI +4.5 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Caffeine+4.5detractor · 95%
- Protein-2.8supporter · 95%
- Alcohol+1.3no signal · 39%
- Lactose+0.9no signal · 26%
- Dietary fat load-0.3no signal · 15%
- Histamine load-0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑75
- DNACYP2D6 poor metabolizer → higher exposure
- DNADPYD *2A → slower clearance
- Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion
- Autonomic recovery ↓20
- WearableShort sleep window
- Mucosal barrier integrity ↓10
- WearableSleep 5.8 h, below personal baseline
DNA
Fictional pharmacogenomic panel
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Poor metabolizerHigher exposure at standard dose
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.7 · butyrate capacity 47/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisHigh
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 43 ms
- Sleep
- 5.8 h
- Steps
- 6,849
- Resting HR
- 69 bpm
Daily log: GI score 18, nutritional resilience 64, adherence 89.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.