Patient P-03300
Therapy response
Stable
Tolerance
Favorable
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Stable
Discontinuation risk
73%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S14
- Day 60 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 69 GI-04 recommended — GI Support Protocol GI-04
- Day 70 Patient accepted — Started GI-04 in the companion
- Day 78 GI symptom burden −38% vs expected — GI Support Protocol GI-04
- Day 84 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 60.
Primary contributors, last 14 days
- GI instability+13
- Inflammatory activity+5
- Nutritional resilience-4
What helped?
- GI Support Protocol GI-04Day 69Result: symptom burden −38%
LIFE OS recommendation
Dosing / Timing Recommendation DT-01
70%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 80% showed improvement
- median effect visible after 5 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log4.2/10
stable · +0.0 vs previous 14 d
Stress level
Daily log5.9/10
stable · +0.0 vs previous 14 d
Pessimism score
Daily log5.3/10
worsening · +0.3 vs previous 14 d
Sleep quality
Wearable46.1/100
stable · -0.8 vs previous 14 d
Libido
Daily log4/10
stable · -0.0 vs previous 14 d
HRV
Wearable44.7 ms
stable · -1.0 vs previous 14 d
Toxicity
Blood29.8/100
improving · -1.4 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 41 from the failing basin, 47 from restoration.
Would help
- ME-01 Monitoring Escalation100% improved among 11 similar · onset 3 d · confidence 73%
- DT-01 Dosing / Timing Recommendation80% improved among 10 similar · onset 5 d · confidence 73%
- CR-01 Clinician Review100% improved among 5 similar · onset 5 d · confidence 73%
- More proteinGI -5.2 next day on high-intake days · n 17
Would not help
- AD-05 Adherence Supportonly 25% improved among 12 similar
- Keep fat lowGI +6.4 next day on high-intake days · n 21
- Keep histamine lowGI +5.2 next day on high-intake days · n 21
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+6.4detractor · 95%
- Histamine load+5.2detractor · 95%
- Protein-5.2supporter · 95%
- Lactose+1.4no signal · 27%
- Alcohol+0.9no signal · 16%
- Caffeine-0.8no signal · 17%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓80
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 47 and rising
- Inflammatory signalling ↑50
- DNAIL6 -174 variant raises baseline inflammatory tone
- BloodInflammatory load index 41
- Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 40/100
- Autonomic recovery ↓25
- WearableResting HR 74 bpm
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.6 · butyrate capacity 40/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 46 ms
- Sleep
- 6.8 h
- Steps
- 6,657
- Resting HR
- 72 bpm
Daily log: GI score 47, nutritional resilience 52, adherence 51.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.