Patient P-03307
Therapy response
Unstable
Tolerance
Improving
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Favorable
Discontinuation risk
13%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S03
- Day 20 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 74 ME-01 recommended — Monitoring Escalation ME-01
- Day 75 Patient accepted — Started ME-01 in the companion
- Day 78 Deterioration detected before clinical escalation — Monitoring Escalation ME-01
What changed?
Trajectory began diverging from predicted response on Day 20.
Primary contributors, last 14 days
- Toxicity-8
- Inflammatory activity-5
- Treatment adherence-2
What helped?
- Monitoring Escalation ME-01Day 74Result: deterioration detected before clinical escalation
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log5.7/10
worsening · -0.3 vs previous 14 d
Stress level
Daily log2.9/10
stable · +0.1 vs previous 14 d
Pessimism score
Daily log4.6/10
stable · +0.1 vs previous 14 d
Sleep quality
Wearable78.2/100
stable · -0.3 vs previous 14 d
Libido
Daily log5.3/10
stable · +0.1 vs previous 14 d
HRV
Wearable69.3 ms
stable · -1.0 vs previous 14 d
Toxicity
Blood10.9/100
worsening · +0.7 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 70 from the failing basin, 61 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -6.7 next day on high-intake days · n 21
Would not help
- AD-05 Adherence Supportonly 29% improved among 14 similar
- Keep caffeine lowGI +4.2 next day on high-intake days · n 23
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-6.7supporter · 95%
- Caffeine+4.2detractor · 95%
- Dietary fat load-2.4no signal · 50%
- Lactose-1.3no signal · 21%
- Alcohol-0.9no signal · 17%
- Histamine load+0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
- Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
- Butyrate / short-chain fatty acid production ↓25
- MicrobiomeF. prausnitzii depleted
- Autonomic recovery ↑25
- WearableResting HR 72 bpm
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 3.9 · butyrate capacity 73/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 67 ms
- Sleep
- 7.9 h
- Steps
- 5,494
- Resting HR
- 75 bpm
Daily log: GI score 16, nutritional resilience 67, adherence 83.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.