Patient P-03475
Therapy response
Stable
Tolerance
Improving
GI state
Improving
Inflammatory state
Improving
Nutritional resilience
Improving
Discontinuation risk
5%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S20
- Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 18 HY-01 recommended — Hydration Protocol HY-01
- Day 19 Patient accepted — Started HY-01 in the companion
- Day 23 GI symptom burden −22% vs expected — Hydration Protocol HY-01
- Day 29 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 14.
Primary contributors, last 14 days
- GI instability-15
- Inflammatory activity-13
- Toxicity-12
- Nutritional resilience+9
- Treatment adherence+3
What helped?
- Hydration Protocol HY-01Day 18Result: symptom burden −22%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log6.4/10
stable · +0.2 vs previous 14 d
Stress level
Daily log2.1/10
stable · +0.1 vs previous 14 d
Pessimism score
Daily log3/10
worsening · +0.2 vs previous 14 d
Sleep quality
Wearable64.7/100
improving · +6.2 vs previous 14 d
Libido
Daily log6.3/10
worsening · -0.2 vs previous 14 d
HRV
Wearable71.6 ms
stable · +1.9 vs previous 14 d
Toxicity
Blood4.4/100
worsening · +4.5 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 78 from the failing basin, 29 from restoration.
Good elements to keep
- Hydration Protocol HY-01intervention · steering +22
- Protein (supports)perturbation · steering +10.2
- Daily walks resumedperturbation · steering +3.3
- Proteinsupporter · GI -4.8 next day
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- FUT2 non-secretorhidden · steering -10.6
- Dietary fat loadperturbation · steering -7.9
- Low microbial diversityhidden · steering -7.7
- Dietary fat loaddetractor · GI +4.7 next day
- Histamine loaddetractor · GI +4.5 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-4.8supporter · 95%
- Dietary fat load+4.7detractor · 95%
- Histamine load+4.5detractor · 95%
- Lactose+4.1detractor · 95%
- Alcohol-1.5no signal · 26%
- Caffeine-0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
- Butyrate / short-chain fatty acid production ↓35
- MicrobiomeButyrate capacity 27/100
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
DNA
Fictional pharmacogenomic panel
- FUT2 rs601338 AA (non-secretor)Reduced mucosal fucosylation
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
Microbiome
Shannon diversity 2.4 · butyrate capacity 27/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 63 ms
- Sleep
- 6.7 h
- Steps
- 5,796
- Resting HR
- 63 bpm
Daily log: GI score 13, nutritional resilience 74, adherence 93.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- Keep the current walking rhythm
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.