Patient P-03494
Therapy response
Unstable
Tolerance
Deteriorating
GI state
Favorable
Inflammatory state
Deteriorating
Nutritional resilience
Improving
Discontinuation risk
21%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 ONX-7 started — Baseline state S18
- Day 98 Trajectory diverged from prediction — Observed response fell below the model's expected path.
What changed?
Trajectory began diverging from predicted response on Day 98.
Primary contributors, last 14 days
- Toxicity+15
- Inflammatory activity+8
- Treatment adherence+6
- Nutritional resilience+5
What helped?
No interventions yet.
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Energy level
Daily log4.8/10
worsening · -0.7 vs previous 14 d
Stress level
Daily log4.4/10
worsening · +0.7 vs previous 14 d
Pessimism score
Daily log5/10
worsening · +0.6 vs previous 14 d
Sleep quality
Wearable13.6/100
worsening · -7.8 vs previous 14 d
Libido
Daily log4.9/10
worsening · -0.6 vs previous 14 d
HRV
Wearable33.3 ms
worsening · -4.2 vs previous 14 d
Toxicity
Blood23/100
worsening · +11.5 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 63 from the failing basin, 41 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -1.9 next day on high-intake days · n 22
Would not help
- AD-05 Adherence Supportonly 29% improved among 14 similar
- Keep alcohol lowGI +2.5 next day on high-intake days · n 15
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Alcohol+2.5detractor · 95%
- Protein-1.9supporter · 85%
- Dietary fat load+0.7no signal · 25%
- Lactose+0.6no signal · 18%
- Caffeine-0.3no signal · 15%
- Histamine load-0.2no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Autonomic recovery ↓65
- WearableResting HR 79 bpm
- Wearable1,641 steps/day
- WearableShort sleep window
- Inflammatory signalling ↑40
- DNAIL6 -174 variant raises baseline inflammatory tone
- WearableHRV 33 ms, trending down
- Drug metabolism and exposure ↑35
- DNADPYD *2A → slower clearance
- Mucosal barrier integrity ↓10
- WearableSleep 5.2 h, below personal baseline
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- DPYD *2A heterozygousSlower drug clearance
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3 · butyrate capacity 55/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeNormal
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 30 ms
- Sleep
- 5.6 h
- Steps
- 3,654
- Resting HR
- 76 bpm
Daily log: GI score 22, nutritional resilience 66, adherence 84.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Avoid known triggers for now: fried or oily food, dairy, alcohol
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the scheduled dose as agreed with your care team
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.