Patient P-02002
Synthetic patientMETA-24 · Day 172 · 55–64 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Stable
GI state
Deteriorating
Inflammatory state
Stable
Nutritional resilience
Declining
Discontinuation risk
75%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 68 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 76 GI-04 recommended — GI Support Protocol GI-04
- Day 77 Patient accepted — Started GI-04 in the companion
- Day 85 GI symptom burden −32% vs expected — GI Support Protocol GI-04
- Day 91 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 68.
Primary contributors, last 14 days
- GI instability+7
- Nutritional resilience-5
- Treatment adherence-4
- Toxicity-3
- Inflammatory activity-2
What helped?
- GI Support Protocol GI-04Day 76Result: symptom burden −32%
LIFE OS recommendation
Monitoring Escalation ME-01
83%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 3 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable4 min
worsening · -2.7 vs previous 14 d
Sleep duration
Wearable5.4 h
stable · -0.2 vs previous 14 d
Energy level
Daily log3.4/10
worsening · -0.3 vs previous 14 d
Steps
Wearable972
worsening · -363 vs previous 14 d
GI burden
Companion52.2/100
worsening · +7.8 vs previous 14 d
Adherence
Companion47.8 %
stable · -1.2 vs previous 14 d
Sleep quality
Wearable11.9/100
worsening · -7.0 vs previous 14 d
Glucose, CGM daily mean
CGM154 mg/dL
stable · +2.5 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 33 from the failing basin, 54 from restoration.
Would help
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 71%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 71%
- SC-12 Supportive Compound69% improved among 26 similar · onset 6 d · confidence 71%
- More proteinGI -2.9 next day on high-intake days · n 20
Would not help
- Keep fat lowGI +2.9 next day on high-intake days · n 18
- Keep caffeine lowGI +2.9 next day on high-intake days · n 15
- Keep simple carbs lowGI +2.7 next day on high-intake days · n 16
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Dietary fat load+2.9detractor · 94%
- Caffeine+2.9detractor · 88%
- Protein-2.9supporter · 95%
- Simple carbohydrates+2.7detractor · 76%
- Ultra-processed food+2.7detractor · 76%
- Insoluble fibre+0.5no signal · 15%
- Histamine load+0.4no signal · 15%
- Alcohol-0.4no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 37/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑65
- WearableResting HR 80 bpm
- Wearable972 steps/day
- WearableShort sleep window
- Mucosal barrier integrity ↓60
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 52 and rising
- WearableSleep 5.4 h, below personal baseline
- Inflammatory signalling ↓60
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 50
- WearableHRV 36 ms, trending down
- Drug metabolism and exposure ↑60
- DNACYP2D6 poor metabolizer → higher exposure
- BloodToxicity index 44
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 2.9 · butyrate capacity 37/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 36 ms
- Sleep
- 5.8 h
- Steps
- 1,181
- Resting HR
- 77 bpm
Daily log: GI score 52, nutritional resilience 44, adherence 48.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02483 | 25% | S06 | BR-03 | no change | 64 |
| P-02087 | 22% | S01 | BR-03 | no change | 40 |
| P-02054 | 35% | S01 | CR-01 | improved | 57 |
| P-02154 | 35% | S16 | CR-01 | improved | 57 |
| P-02009 | 33% | S08 | CR-01 | improved | 64 |
| P-02151 | 33% | S04 | CR-01 | improved | 49 |
| P-02025 | 31% | S15 | CR-01 | improved | 61 |
| P-02233 | 31% | S16 | CR-01 | improved | 66 |
| P-02274 | 23% | S15 | DT-01 | improved | 50 |
| P-02339 | 23% | S03 | DT-01 | improved | 50 |
| P-02395 | 23% | S12 | DT-01 | improved | 57 |
| P-02491 | 23% | S09 | DT-01 | no change | 65 |