Patient P-02014
Therapy response
Stable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
73%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 71 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 79 GI-04 recommended — GI Support Protocol GI-04
- Day 80 Patient accepted — Started GI-04 in the companion
- Day 88 GI symptom burden −23% vs expected — GI Support Protocol GI-04
- Day 94 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 71.
Primary contributors, last 14 days
- Inflammatory activity-23
- GI instability-13
- Toxicity-11
- Nutritional resilience+3
What helped?
- GI Support Protocol GI-04Day 79Result: symptom burden −23%
LIFE OS recommendation
Monitoring Escalation ME-01
89%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 3 days
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 48
- WearableHRV 19 ms, trending down
- Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 62 and rising
- Butyrate / short-chain fatty acid production ↓45
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑45
- WearableResting HR 75 bpm
- Wearable3,092 steps/day
- Drug metabolism and exposure ↑20
- BloodToxicity index 43
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 3 · butyrate capacity 46/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 18 ms
- Sleep
- 6.9 h
- Steps
- 1,522
- Resting HR
- 74 bpm
Daily log: GI score 62, nutritional resilience 33, adherence 45.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02018 | 41% | S01 | GI-04 | improved | 46 |
| P-02410 | 35% | S01 | GI-04 | improved | 55 |
| P-02054 | 30% | S01 | CR-01 | improved | 57 |
| P-02409 | 30% | S01 | SC-12 | no change | 54 |
| P-02307 | 21% | S01 | — | — | 55 |
| P-02598 | 20% | S01 | — | — | 53 |
| P-02041 | 19% | S01 | — | — | 27 |
| P-02276 | 19% | S01 | — | — | 57 |
| P-02375 | 19% | S01 | — | — | 44 |
| P-02550 | 19% | S01 | — | — | 70 |
| P-02568 | 19% | S01 | — | — | 51 |
| P-02662 | 19% | S01 | — | — | 20 |