Patient P-02014
Synthetic patientMETA-24 · Day 169 · 65–74 · M · baseline S14Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Unstable
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
73%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S14
- Day 71 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 79 GI-04 recommended — GI Support Protocol GI-04
- Day 80 Patient accepted — Started GI-04 in the companion
- Day 88 GI symptom burden −23% vs expected — GI Support Protocol GI-04
- Day 94 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 71.
Primary contributors, last 14 days
- Inflammatory activity-23
- GI instability-13
- Toxicity-11
- Nutritional resilience+3
What helped?
- GI Support Protocol GI-04Day 79Result: symptom burden −23%
LIFE OS recommendation
Monitoring Escalation ME-01
89%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 3 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable29 min
stable · +0.1 vs previous 14 d
Sleep duration
Wearable6.8 h
stable · -0.1 vs previous 14 d
Energy level
Daily log3.6/10
improving · +0.3 vs previous 14 d
Steps
Wearable3,092
improving · +202 vs previous 14 d
GI burden
Companion62.4/100
stable · -0.7 vs previous 14 d
Adherence
Companion44.5 %
stable · -0.5 vs previous 14 d
Sleep quality
Wearable35.2/100
worsening · -1.4 vs previous 14 d
Glucose, CGM daily mean
CGM138 mg/dL
stable · -2.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards restoration · 33 from the failing basin, 60 from restoration.
Would help
- ME-01 Monitoring Escalation100% improved among 42 similar · onset 3 d · confidence 77%
- NP-02 Dietary Support Protocol59% improved among 32 similar · onset 10 d · confidence 77%
- SC-12 Supportive Compound69% improved among 26 similar · onset 6 d · confidence 77%
- More proteinGI -4.3 next day on high-intake days · n 16
Would not help
- Keep fibre lowGI +2.8 next day on high-intake days · n 17
- Keep ultra-processed lowGI +1.9 next day on high-intake days · n 21
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-4.3supporter · 95%
- Insoluble fibre+2.8detractor · 87%
- Ultra-processed food+1.9detractor · 64%
- Caffeine+1no signal · 34%
- Alcohol+0.5no signal · 15%
- Dietary fat load+0.4no signal · 15%
- Histamine load-0.2no signal · 15%
- Simple carbohydrates-0.1no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 48
- WearableHRV 19 ms, trending down
- Mucosal barrier integrity ↓50
- MicrobiomeAkkermansia low → thinner mucus layer
- Daily logGI symptom score 62 and rising
- Butyrate / short-chain fatty acid production ↓45
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Autonomic recovery ↑45
- WearableResting HR 75 bpm
- Wearable3,092 steps/day
- Drug metabolism and exposure ↑20
- BloodToxicity index 43
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- GLP1R rs6923761 AAltered receptor sensitivity
Microbiome
Shannon diversity 3 · butyrate capacity 46/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 18 ms
- Sleep
- 6.9 h
- Steps
- 1,522
- Resting HR
- 74 bpm
Daily log: GI score 62, nutritional resilience 33, adherence 45.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02552 | 19% | S07 | AD-05 | no change | 29 |
| P-02093 | 18% | S05 | AD-05 | no change | 40 |
| P-02483 | 20% | S06 | BR-03 | no change | 64 |
| P-02564 | 19% | S15 | BR-03 | improved | 32 |
| P-02087 | 18% | S01 | BR-03 | no change | 40 |
| P-02025 | 33% | S15 | CR-01 | improved | 61 |
| P-02151 | 33% | S04 | CR-01 | improved | 49 |
| P-02054 | 30% | S01 | CR-01 | improved | 57 |
| P-02009 | 27% | S08 | CR-01 | improved | 64 |
| P-02154 | 27% | S16 | CR-01 | improved | 57 |
| P-02233 | 25% | S16 | CR-01 | improved | 66 |
| P-02395 | 20% | S12 | DT-01 | improved | 57 |