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Patient P-02023

Synthetic patientMETA-24 · Day 137 · 25–34 · F · baseline S07Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
40%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S07
  2. Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 22 HY-01 recommended — Hydration Protocol HY-01
  4. Day 23 Patient declined — Not now

What changed?

Trajectory began diverging from predicted response on Day 14.

Primary contributors, last 14 days
  • GI instability+13
  • Inflammatory activity+7
  • Toxicity+7
  • Nutritional resilience-5
  • Treatment adherence-5

What helped?

  • Hydration Protocol HY-01Day 22
    Declined by patient
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes
Wearable
40 min
worsening · -6.1 vs previous 14 d
Sleep duration
Wearable
6 h
stable · -0.2 vs previous 14 d
Energy level
Daily log
4.8/10
worsening · -0.4 vs previous 14 d
Steps
Wearable
4,483
worsening · -412 vs previous 14 d
GI burden
Companion
35.2/100
worsening · +2.5 vs previous 14 d
Adherence
Companion
85.6 %
stable · -3.7 vs previous 14 d
Sleep quality
Wearable
32.2/100
worsening · -2.3 vs previous 14 d
Glucose, CGM daily mean
CGM
143 mg/dL
stable · -0.1 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →

Heading towards failing · 50 from the failing basin, 39 from restoration.

Would help
  • No untried action with strong evidence. Compose one from primitives.
  • More protein
    GI -7.6 next day on high-intake days · n 24
Would not help
  • BR-03 Behavioural Recommendation
    only 25% improved among 8 similar
  • Keep caffeine low
    GI +7.6 next day on high-intake days · n 20
  • Keep histamine low
    GI +6.9 next day on high-intake days · n 19
  • Keep fat low
    GI +6.7 next day on high-intake days · n 17
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Caffeine
    +7.6detractor · 95%
  • Protein
    -7.6supporter · 95%
  • Histamine load
    +6.9detractor · 95%
  • Dietary fat load
    +6.7detractor · 95%
  • Simple carbohydrates
    +5.8detractor · 95%
  • Ultra-processed food
    +4.8detractor · 95%
  • Alcohol
    +1no signal · 17%
  • Insoluble fibre
    -0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Mucosal barrier integrity ↓70
    • DNAFUT2 non-secretor lowers mucosal fucosylation
    • MicrobiomeAkkermansia low → thinner mucus layer
    • WearableSleep 6.0 h, below personal baseline
  • Autonomic recovery ↓45
    • WearableResting HR 78 bpm
    • WearableShort sleep window
  • Drug metabolism and exposure ↑40
    • DNACYP2D6 poor metabolizer → higher exposure
  • Butyrate / short-chain fatty acid production ↓35
    • MicrobiomeButyrate capacity 31/100
  • Inflammatory signalling ↑15
    • WearableHRV 33 ms, trending down
DNA
Fictional pharmacogenomic panel
  • FUT2 rs601338 AA (non-secretor)
    Reduced mucosal fucosylation
  • CYP2D6 Poor metabolizer
    Higher exposure at standard dose
Microbiome
Shannon diversity 2 · butyrate capacity 31/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisNormal
  • Bifidobacterium longumLow
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
39 ms
Sleep
7.1 h
Steps
6,634
Resting HR
76 bpm
Daily log: GI score 35, nutritional resilience 57, adherence 86.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
  • Log the daily check-in; one line is enough
  • A 15-minute walk after lunch
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the dose at the same time relative to your evening meal
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0269831%S06ME-01improved71
P-0255331%S13——71
P-0240333%S03——71
P-0255031%S01——70
P-0219231%S05——69
P-0221431%S08SC-12no change69
P-0208332%S13——69
P-0229332%S15HY-01no change68
P-0209033%S04——68
P-0251833%S17DT-01improved68
P-0260433%S03——67
P-0219435%S03——67