Patient P-02035
Synthetic patientMETA-24 · Day 170 · 25–34 · F · baseline S19Steering view · 3DOpen companion preview
Therapy response
Improving
Tolerance
Improving
GI state
Stable
Inflammatory state
Improving
Nutritional resilience
Unstable
Discontinuation risk
59%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S19
- Day 70 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 76 GI-04 recommended — GI Support Protocol GI-04
- Day 77 Patient accepted — Started GI-04 in the companion
- Day 85 GI symptom burden −27% vs expected — GI Support Protocol GI-04
- Day 91 Tolerance state changed — Unstable → Improving
What changed?
Trajectory began diverging from predicted response on Day 70.
Primary contributors, last 14 days
- Inflammatory activity-12
- Treatment adherence-8
- GI instability-4
- Toxicity-4
What helped?
- GI Support Protocol GI-04Day 76Result: symptom burden −27%
LIFE OS recommendation
Monitoring Escalation ME-01
80%
probability of meaningful tolerance improvement
- 284 similar trajectories
- 100% showed improvement
- median effect visible after 3 days
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Active minutes
Wearable34 min
worsening · -1.5 vs previous 14 d
Sleep duration
Wearable7.7 h
stable · +0.1 vs previous 14 d
Energy level
Daily log4.1/10
improving · +0.3 vs previous 14 d
Steps
Wearable3,356
worsening · -436 vs previous 14 d
GI burden
Companion54.1/100
worsening · +2.6 vs previous 14 d
Adherence
Companion43.4 %
worsening · -8.4 vs previous 14 d
Sleep quality
Wearable37.5/100
stable · -0.7 vs previous 14 d
Glucose, CGM daily mean
CGM138 mg/dL
stable · -0.7 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →Heading towards restoration · 40 from the failing basin, 50 from restoration.
Good elements to keep
- GI Support Protocol GI-04intervention · steering +38.3
- Protein (supports)perturbation · steering +7
- Proteinsupporter · GI -4.1 next day
Main detractors to watch
- Low butyrate capacityhidden · steering -17.5
- Dietary fat loadperturbation · steering -7.5
- Bacteroides fragilis elevatedhidden · steering -7.4
- IL6 high-expression varianthidden · steering -7.3
- Dietary fat loaddetractor · GI +3.9 next day
- Ultra-processed fooddetractor · GI +3.5 next day
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-4.1supporter · 95%
- Dietary fat load+3.9detractor · 95%
- Ultra-processed food+3.5detractor · 95%
- Insoluble fibre-2no signal · 48%
- Alcohol-1.1no signal · 32%
- Caffeine-0.9no signal · 22%
- Simple carbohydrates-0.7no signal · 17%
- Histamine load+0.3no signal · 15%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Inflammatory signalling ↓85
- DNAIL6 -174 variant raises baseline inflammatory tone
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 45
- WearableHRV 18 ms, trending down
- Butyrate / short-chain fatty acid production ↓80
- MicrobiomeButyrate capacity 34/100
- MicrobiomeF. prausnitzii depleted
- Daily logFibre intake low in recent food logs
- Mucosal barrier integrity ↓20
- Daily logGI symptom score 54 and rising
- Drug metabolism and exposure ↑20
- BloodToxicity index 43
- Autonomic recovery ↑20
- Wearable3,356 steps/day
DNA
Fictional pharmacogenomic panel
- IL6 -174 G/CHigher inflammatory tone
- CYP2D6 Normal metabolizerExpected exposure
- MTHFR C677TReduced folate turnover
Microbiome
Shannon diversity 3.1 · butyrate capacity 34/100
- Akkermansia muciniphilaNormal
- Faecalibacterium prausnitziiLow
- Bacteroides fragilisHigh
- Bifidobacterium longumNormal
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 20 ms
- Sleep
- 7.1 h
- Steps
- 3,530
- Resting HR
- 67 bpm
Daily log: GI score 54, nutritional resilience 42, adherence 43.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
- Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
- Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Track each bowel movement today: time, stool form, urgency, overnight waking
- A 15-minute walk after lunch
- Keep the sleep window steady
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- Electrolyte solution, one sachet after any loose stool
- Fictional demo item: oral nutrition supplement with lunch
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02633 | 54% | S14 | NP-02 | improved | 48 |
| P-02014 | 49% | S14 | GI-04 | improved | 48 |
| P-02574 | 46% | S14 | ME-01 | improved | 45 |
| P-02002 | 45% | S14 | GI-04 | improved | 47 |
| P-02241 | 45% | S09 | GI-04 | improved | 56 |
| P-02363 | 45% | S14 | GI-04 | improved | 49 |
| P-02118 | 44% | S14 | GI-04 | improved | 47 |
| P-02108 | 42% | S14 | GI-04 | improved | 43 |
| P-02125 | 42% | S14 | GI-04 | improved | 55 |
| P-02542 | 42% | S14 | NP-02 | improved | 44 |
| P-02268 | 41% | S14 | GI-04 | improved | 43 |
| P-02297 | 41% | S02 | NP-02 | improved | 49 |