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Patient P-02037

Synthetic patientMETA-24 · Day 178 · 75+ · M · baseline S04Steering view · 3DOpen companion preview
Therapy response
Stable
Tolerance
Improving
GI state
Favorable
Inflammatory state
Improving
Nutritional resilience
Stable
Discontinuation risk
20%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S04
  2. Day 16 Trajectory diverged from prediction — Observed response fell below the model's expected path.
  3. Day 22 GI-04 recommended — GI Support Protocol GI-04
  4. Day 23 Patient accepted — Started GI-04 in the companion
  5. Day 31 GI symptom burden −11% vs expected — GI Support Protocol GI-04
  6. Day 37 Tolerance state changed — Unstable → Improving

What changed?

Trajectory began diverging from predicted response on Day 16.

Primary contributors, last 14 days
  • GI instability+4
  • Inflammatory activity-4
  • Nutritional resilience+4
  • Treatment adherence+4
  • Toxicity-4

What helped?

  • GI Support Protocol GI-04Day 22
    Result: symptom burden −11%
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes
Wearable
80 min
stable · +1.8 vs previous 14 d
Sleep duration
Wearable
5.5 h
stable · 0.0 vs previous 14 d
Energy level
Daily log
4.6/10
stable · +0.0 vs previous 14 d
Steps
Wearable
9,082
stable · +223 vs previous 14 d
GI burden
Companion
23.3/100
improving · -5.1 vs previous 14 d
Adherence
Companion
95.5 %
stable · +3.5 vs previous 14 d
Sleep quality
Wearable
20.1/100
stable · +0.3 vs previous 14 d
Glucose, CGM daily mean
CGM
137 mg/dL
stable · -2.5 vs previous 14 d
This trajectory is doing well — what to keep, what to watch
Steering view →

Heading towards restoration · 65 from the failing basin, 27 from restoration.

Good elements to keep
  • GI Support Protocol GI-04
    intervention · steering +7.2
  • Protein (supports)
    perturbation · steering +4.2
  • Protein
    supporter · GI -2.6 next day
Main detractors to watch
  • Low butyrate capacity
    hidden · steering -17.5
  • FUT2 non-secretor
    hidden · steering -10.6
  • Enterobacteriaceae elevated
    hidden · steering -7.4
  • Histamine load
    perturbation · steering -5.3
  • Histamine load
    detractor · GI +3.2 next day
  • Dietary fat load
    detractor · GI +2.5 next day
State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

  • Histamine load
    +3.2detractor · 95%
  • Protein
    -2.6supporter · 81%
  • Dietary fat load
    +2.5detractor · 90%
  • Insoluble fibre
    +1.5no signal · 48%
  • Caffeine
    +0.4no signal · 15%
  • Ultra-processed food
    -0.4no signal · 15%
  • Simple carbohydrates
    -0.3no signal · 15%
  • Alcohol
    +0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure
  • Mucosal barrier integrity ↓70
    • DNAFUT2 non-secretor lowers mucosal fucosylation
    • MicrobiomeAkkermansia low → thinner mucus layer
    • WearableSleep 5.5 h, below personal baseline
  • Butyrate / short-chain fatty acid production ↓35
    • MicrobiomeButyrate capacity 30/100
  • Autonomic recovery ↑20
    • WearableShort sleep window
  • Inflammatory signalling ↓15
    • WearableHRV 32 ms, trending down
DNA
Fictional pharmacogenomic panel
  • FUT2 rs601338 AA (non-secretor)
    Reduced mucosal fucosylation
  • CYP2D6 Normal metabolizer
    Expected exposure
Microbiome
Shannon diversity 3.1 · butyrate capacity 30/100
  • Akkermansia muciniphilaLow
  • Faecalibacterium prausnitziiNormal
  • Bacteroides fragilisNormal
  • Bifidobacterium longumNormal
  • EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
HRV
31 ms
Sleep
6.6 h
Steps
8,972
Resting HR
70 bpm
Daily log: GI score 23, nutritional resilience 59, adherence 96.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview
What to eat
  • Keep meals regular; three to four moderate portions spaced through the day
  • Include a cooked vegetable portion with each main meal
  • Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
  • Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
  • Log the daily check-in; one line is enough
  • Keep the current walking rhythm
  • Protect a 7.5-hour sleep window; screens off 30 minutes before
  • Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
  • Take the dose at the same time relative to your evening meal
  • No additional supplements this week
  • Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
PatientSimilarityBaselineInterventionOutcomeResponse today
P-0235433%S01CR-01improved78
P-0269836%S06ME-01improved71
P-0255336%S13——71
P-0240333%S03——71
P-0255036%S01——70
P-0219236%S05——69
P-0221436%S08SC-12no change69
P-0235632%S08——69
P-0208334%S13——69
P-0229338%S15HY-01no change68
P-0209042%S04——68
P-0251836%S17DT-01improved68