700 patients110,866 observations180 daysLIVE
← Patients

Patient P-02043

Synthetic patientMETA-24 · Day 143 · 25–34 · M · baseline S06Steering view · 3DOpen companion preview
Therapy response
Declining
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Stable
Discontinuation risk
34%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events
solid = observed · dashed = predicted
  1. Day 0 META-24 started — Baseline state S06
  2. Day 14 Trajectory diverged from prediction — Observed response fell below the model's expected path.

What changed?

Trajectory began diverging from predicted response on Day 14.

Primary contributors, last 14 days
  • GI instability+9
  • Toxicity+9
  • Inflammatory activity+8
  • Nutritional resilience-3

What helped?

No interventions yet.

    LIFE OS recommendation
    No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

    Daily trackers

    Molecule settings

    The trackers this program marks as important, last 14 days vs the 14 before.

    Active minutes
    Wearable
    96 min
    stable · -1.4 vs previous 14 d
    Sleep duration
    Wearable
    5.6 h
    stable · +0.1 vs previous 14 d
    Energy level
    Daily log
    5.4/10
    stable · -0.1 vs previous 14 d
    Steps
    Wearable
    9,553
    stable · +120 vs previous 14 d
    GI burden
    Companion
    34.5/100
    improving · -6.2 vs previous 14 d
    Adherence
    Companion
    95.5 %
    stable · +0.2 vs previous 14 d
    Sleep quality
    Wearable
    27.7/100
    improving · +1.8 vs previous 14 d
    Glucose, CGM daily mean
    CGM
    133 mg/dL
    stable · -5.4 vs previous 14 d
    This trajectory is decaying — what would help, what would not
    Steering view →

    Heading towards failing · 63 from the failing basin, 25 from restoration.

    Would help
    • No untried action with strong evidence. Compose one from primitives.
    • More protein
      GI -6.2 next day on high-intake days · n 23
    Would not help
    • Keep histamine low
      GI +6.5 next day on high-intake days · n 20
    • Keep fibre low
      GI +3.7 next day on high-intake days · n 18
    State influencers · digestive

    Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

    • Histamine load
      +6.5detractor · 95%
    • Protein
      -6.2supporter · 95%
    • Dietary fat load
      -4.4no signal · 53%
    • Insoluble fibre
      +3.7detractor · 79%
    • Simple carbohydrates
      +1.7no signal · 32%
    • Caffeine
      -1no signal · 19%
    • Ultra-processed food
      -1no signal · 16%
    • Alcohol
      -0.4no signal · 15%

    Biological layers

    Which pathways look influenced, and by which layer of this person's biology.

    Pathways under pressure
    • Mucosal barrier integrity ↓70
      • DNAFUT2 non-secretor lowers mucosal fucosylation
      • MicrobiomeAkkermansia low → thinner mucus layer
      • WearableSleep 5.6 h, below personal baseline
    • Inflammatory signalling ↑35
      • MicrobiomeBacteroides fragilis expansion
      • WearableHRV 37 ms, trending down
    • Autonomic recovery ↓20
      • WearableShort sleep window
    DNA
    Fictional pharmacogenomic panel
    • FUT2 rs601338 AA (non-secretor)
      Reduced mucosal fucosylation
    • CYP2D6 Normal metabolizer
      Expected exposure
    Microbiome
    Shannon diversity 3.1 · butyrate capacity 66/100
    • Akkermansia muciniphilaLow
    • Faecalibacterium prausnitziiNormal
    • Bacteroides fragilisHigh
    • Bifidobacterium longumLow
    • EnterobacteriaceaeNormal
    Wearable, last 14 days
    daily evolution fed into the runtime
    HRV
    39 ms
    Sleep
    6.1 h
    Steps
    9,341
    Resting HR
    60 bpm
    Daily log: GI score 35, nutritional resilience 55, adherence 96.

    What this patient sees in NostraAI

    The content that steers the trajectory: what to eat, what to do, what to take.

    Open companion preview
    What to eat
    • Keep meals regular; three to four moderate portions spaced through the day
    • Include a cooked vegetable portion with each main meal
    • Keep fibre steady; no new sources this week
    • Eat slowly and stop at comfortable fullness — smaller volume, more often
    What to do
    • Log the daily check-in; one line is enough
    • Keep the current walking rhythm
    • Protect a 7.5-hour sleep window; screens off 30 minutes before
    • Keep hydration steady: small amounts through the day rather than large volumes at once
    What to take
    • Take the dose at the same time relative to your evening meal
    • No additional supplements this week
    • Fictional demo item: continue vitamin D as before

    284 biologically similar trajectories

    Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

    Sort by similaritySort by interventionSort by outcomeSort by stateSort by response
    PatientSimilarityBaselineInterventionOutcomeResponse today
    P-0251845%S17DT-01improved68
    P-0246241%S12DT-01improved65
    P-0253841%S02GI-04improved59
    P-0259941%S14HY-01improved54
    P-0262041%S01HY-01improved64
    P-0203340%S06GI-04improved51
    P-0269840%S06ME-01improved71
    P-0203739%S04GI-04improved53
    P-0227439%S15DT-01improved50
    P-0235439%S01CR-01improved78
    P-0206438%S04SC-12improved57
    P-0212638%S16DT-01improved59