Patient P-02054

Synthetic patientMETA-24 · Day 171 · 65–74 · F · baseline S01Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Stable

GI state

Deteriorating

Inflammatory state

Stable

Nutritional resilience

Declining

Discontinuation risk

49%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S01
Day 119 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 122 CR-01 recommended — Clinician Review CR-01
Day 123 Patient accepted — Started CR-01 in the companion
Day 128 Deterioration detected before clinical escalation — Clinician Review CR-01

What changed?

Trajectory began diverging from predicted response on Day 119.

Primary contributors, last 14 days

Nutritional resilience-8
GI instability+4
Inflammatory activity+3
Treatment adherence-2

What helped?

Clinician Review CR-01Day 122
Result: deterioration detected before clinical escalation

LIFE OS recommendation

GI Support Protocol GI-04

57%

probability of meaningful tolerance improvement

284 similar trajectories
89% showed improvement
median effect visible after 8 days

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

60 min

stable · +0.6 vs previous 14 d

Sleep duration

Wearable

7 h

stable · +0.2 vs previous 14 d

Energy level

Daily log

3.3/10

improving · +0.3 vs previous 14 d

Steps

Wearable

6,216

stable · +32 vs previous 14 d

GI burden

Companion

43.4/100

improving · -2.9 vs previous 14 d

Adherence

Companion

74.4 %

worsening · -5.0 vs previous 14 d

Sleep quality

Wearable

43.1/100

improving · +2.8 vs previous 14 d

Glucose, CGM daily mean

CGM

137 mg/dL

stable · +1.9 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards failing · 44 from the failing basin, 44 from restoration.

Would help

GI-04 GI Support Protocol
77% improved among 64 similar · onset 8 d · confidence 51%
ME-01 Monitoring Escalation
100% improved among 42 similar · onset 3 d · confidence 59%
NP-02 Dietary Support Protocol
59% improved among 32 similar · onset 10 d · confidence 59%
More protein
GI -5.1 next day on high-intake days · n 16

Would not help

Keep simple carbs low
GI +3.6 next day on high-intake days · n 15
Keep alcohol low
GI +3.6 next day on high-intake days · n 23
Keep ultra-processed low
GI +3.1 next day on high-intake days · n 15

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Protein
-5.1supporter · 95%
Simple carbohydrates
+3.6detractor · 95%
Alcohol
+3.6detractor · 95%
Ultra-processed food
+3.1detractor · 95%
Histamine load
+1.1no signal · 32%
Insoluble fibre
+0.9no signal · 23%
Caffeine
-0.7no signal · 16%
Dietary fat load
+0.2no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Inflammatory signalling ↑45
- MicrobiomeBacteroides fragilis expansion
- BloodInflammatory load index 52
Autonomic recovery ↓25
- WearableResting HR 77 bpm
Butyrate / short-chain fatty acid production ↓20
- Daily logFibre intake low in recent food logs
Drug metabolism and exposure ↑20
- BloodToxicity index 49

DNA

Fictional pharmacogenomic panel

CYP2D6 Normal metabolizer
Expected exposure

Microbiome

Shannon diversity 2.3 · butyrate capacity 48/100

Akkermansia muciniphilaNormal
Faecalibacterium prausnitziiNormal
Bacteroides fragilisHigh
Bifidobacterium longumNormal
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 43 ms
Sleep: 7.0 h
Steps: 5,633
Resting HR: 79 bpm

Daily log: GI score 43, nutritional resilience 43, adherence 74.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Prepare a plain, low-fat pasta or rice meal and note how it feels afterwards
Choose a freshly cooked, lean protein; avoid frying, rich sauces and leftovers for now
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Track each bowel movement today: time, stool form, urgency, overnight waking
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
Electrolyte solution, one sachet after any loose stool
Fictional demo item: oral nutrition supplement with lunch

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02483	27%	S06	BR-03	no change	64
P-02009	43%	S08	CR-01	improved	64
P-02233	42%	S16	CR-01	improved	66
P-02025	41%	S15	CR-01	improved	61
P-02151	41%	S04	CR-01	improved	49
P-02154	40%	S16	CR-01	improved	57
P-02395	26%	S12	DT-01	improved	57
P-02491	26%	S09	DT-01	no change	65
P-02274	25%	S15	DT-01	improved	50
P-02339	25%	S03	DT-01	improved	50
P-02462	24%	S12	DT-01	improved	65
P-02518	24%	S17	DT-01	improved	68