Patient P-02058

Synthetic patientMETA-24 · Day 142 · 25–34 · M · baseline S05Steering view · 3D Open companion preview

Therapy response

Improving

Tolerance

Favorable

GI state

Improving

Inflammatory state

Favorable

Nutritional resilience

Improving

Discontinuation risk

12%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S05
Day 15 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 22 GI-04 recommended — GI Support Protocol GI-04
Day 23 Patient accepted — Started GI-04 in the companion
Day 31 No meaningful change — GI Support Protocol GI-04

What changed?

Trajectory began diverging from predicted response on Day 15.

Primary contributors, last 14 days

GI instability-10
Nutritional resilience+8
Treatment adherence+5
Inflammatory activity-3
Toxicity+3

What helped?

GI Support Protocol GI-04Day 22
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

72 min

stable · -1.6 vs previous 14 d

Sleep duration

Wearable

6.2 h

stable · +0.2 vs previous 14 d

Energy level

Daily log

5.8/10

improving · +0.2 vs previous 14 d

Steps

Wearable

7,690

stable · -46 vs previous 14 d

GI burden

Companion

13.9/100

improving · -6.8 vs previous 14 d

Adherence

Companion

93.1 %

improving · +4.4 vs previous 14 d

Sleep quality

Wearable

33.2/100

improving · +5.5 vs previous 14 d

Glucose, CGM daily mean

CGM

132 mg/dL

stable · -1.6 vs previous 14 d

This trajectory is doing well — what to keep, what to watch

Steering view →

Heading towards restoration · 71 from the failing basin, 31 from restoration.

Good elements to keep

Protein (supports)
perturbation · steering +8
GI Support Protocol GI-04
intervention · steering +7.3
Daily walks resumed
perturbation · steering +3.3
Protein
supporter · GI -4.2 next day

Main detractors to watch

Low butyrate capacity
hidden · steering -17.5
FUT2 non-secretor
hidden · steering -10.6
Rapid metabolizer
hidden · steering -8
Low microbial diversity
hidden · steering -7.7
Dietary fat load
detractor · GI +4.9 next day
Histamine load
detractor · GI +3.4 next day

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Dietary fat load
+4.9detractor · 95%
Protein
-4.2supporter · 95%
Histamine load
+3.4detractor · 95%
Simple carbohydrates
+2.9detractor · 85%
Caffeine
+2.9detractor · 80%
Ultra-processed food
+2.7detractor · 78%
Insoluble fibre
+2no signal · 52%
Alcohol
-0.1no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Mucosal barrier integrity ↓60
- DNAFUT2 non-secretor lowers mucosal fucosylation
- MicrobiomeAkkermansia low → thinner mucus layer
Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 30/100
- MicrobiomeF. prausnitzii depleted
Autonomic recovery ↑20
- WearableShort sleep window
Inflammatory signalling ↓15
- WearableHRV 37 ms, trending down

DNA

Fictional pharmacogenomic panel

FUT2 rs601338 AA (non-secretor)
Reduced mucosal fucosylation
CYP2D6 Rapid metabolizer
Expected exposure
MTHFR C677T
Reduced folate turnover

Microbiome

Shannon diversity 2.9 · butyrate capacity 30/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisNormal
Bifidobacterium longumLow
EnterobacteriaceaeHigh

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 35 ms
Sleep: 6.0 h
Steps: 7,651
Resting HR: 59 bpm

Daily log: GI score 14, nutritional resilience 66, adherence 93.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Protect a 7.5-hour sleep window; screens off 30 minutes before
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02568	41%	S01	—	—	51
P-02307	39%	S01	—	—	55
P-02218	38%	S01	DT-01	improved	61
P-02598	38%	S01	—	—	53
P-02087	37%	S01	BR-03	no change	40
P-02276	36%	S01	—	—	57
P-02522	35%	S01	BR-03	no change	40
P-02681	35%	S01	—	—	51
P-02437	34%	S01	—	—	64
P-02620	34%	S01	HY-01	improved	64
P-02217	33%	S01	—	—	61
P-02375	33%	S01	—	—	44