Patient P-02063
Therapy response
Stable
Tolerance
Deteriorating
GI state
Deteriorating
Inflammatory state
Deteriorating
Nutritional resilience
Declining
Discontinuation risk
31%
Trajectory
Baseline → today → 30-day prediction · hover a day for signals and eventssolid = observed · dashed = predicted
- Day 0 META-24 started — Baseline state S03
- Day 28 Trajectory diverged from prediction — Observed response fell below the model's expected path.
- Day 132 GI-04 recommended — GI Support Protocol GI-04
- Day 133 Patient accepted — Started GI-04 in the companion
- Day 141 No meaningful change — GI Support Protocol GI-04
What changed?
Trajectory began diverging from predicted response on Day 28.
Primary contributors, last 14 days
- Nutritional resilience-13
- Inflammatory activity+11
- GI instability+8
- Toxicity+6
- Treatment adherence-4
What helped?
- GI Support Protocol GI-04Day 132Result: no meaningful change
LIFE OS recommendation
No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.
Daily trackers
Molecule settingsThe trackers this program marks as important, last 14 days vs the 14 before.
Glucose, CGM daily mean
CGM137 mg/dL
stable · +3.6 vs previous 14 d
Active minutes
Wearable36 min
worsening · -4.4 vs previous 14 d
Sleep duration
Wearable5.6 h
stable · +0.0 vs previous 14 d
Energy level
Daily log5.1/10
stable · +0.1 vs previous 14 d
Steps
Wearable3,621
worsening · -334 vs previous 14 d
GI burden
Companion25.3/100
worsening · +0.9 vs previous 14 d
Adherence
Companion91.5 %
stable · +1.5 vs previous 14 d
This trajectory is decaying — what would help, what would not
Steering view →Heading towards failing · 64 from the failing basin, 24 from restoration.
Would help
- No untried action with strong evidence. Compose one from primitives.
- More proteinGI -6.8 next day on high-intake days · n 22
- More simple carbsGI -3.2 next day on high-intake days · n 14
Would not help
- GI-04 GI Support Protocolalready tried, no meaningful change
- Keep alcohol lowGI +4.8 next day on high-intake days · n 28
- Keep fibre lowGI +4.5 next day on high-intake days · n 11
State influencers · digestive
Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.
- Protein-6.8supporter · 95%
- Alcohol+4.8detractor · 95%
- Insoluble fibre+4.5detractor · 95%
- Simple carbohydrates-3.2supporter · 59%
- Dietary fat load+2no signal · 43%
- Ultra-processed food+1.3no signal · 22%
Biological layers
Which pathways look influenced, and by which layer of this person's biology.
Pathways under pressure
- Mucosal barrier integrity ↓40
- MicrobiomeAkkermansia low → thinner mucus layer
- WearableSleep 5.6 h, below personal baseline
- Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
- Autonomic recovery ↓40
- Wearable3,621 steps/day
- WearableShort sleep window
- Inflammatory signalling ↑15
- WearableHRV 37 ms, trending down
DNA
Fictional pharmacogenomic panel
- CYP2D6 Poor metabolizerHigher exposure at standard dose
Microbiome
Shannon diversity 3 · butyrate capacity 55/100
- Akkermansia muciniphilaLow
- Faecalibacterium prausnitziiNormal
- Bacteroides fragilisNormal
- Bifidobacterium longumLow
- EnterobacteriaceaeHigh
Wearable, last 14 days
daily evolution fed into the runtime
- HRV
- 36 ms
- Sleep
- 6.1 h
- Steps
- 4,103
- Resting HR
- 59 bpm
Daily log: GI score 25, nutritional resilience 56, adherence 92.
What this patient sees in NostraAI
The content that steers the trajectory: what to eat, what to do, what to take.
What to eat
- Keep meals regular; three to four moderate portions spaced through the day
- Include a cooked vegetable portion with each main meal
- Keep fibre steady; no new sources this week
- Eat slowly and stop at comfortable fullness — smaller volume, more often
What to do
- Log the daily check-in; one line is enough
- A 15-minute walk after lunch
- Protect a 7.5-hour sleep window; screens off 30 minutes before
- Keep hydration steady: small amounts through the day rather than large volumes at once
What to take
- Take the dose at the same time relative to your evening meal
- No additional supplements this week
- Fictional demo item: continue vitamin D as before
284 biologically similar trajectories
Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.
| Patient | Similarity | Baseline | Intervention | Outcome | Response today |
|---|---|---|---|---|---|
| P-02064 | 42% | S04 | SC-12 | improved | 57 |
| P-02462 | 42% | S12 | DT-01 | improved | 65 |
| P-02274 | 41% | S15 | DT-01 | improved | 50 |
| P-02339 | 41% | S03 | DT-01 | improved | 50 |
| P-02518 | 41% | S17 | DT-01 | improved | 68 |
| P-02538 | 41% | S02 | GI-04 | improved | 59 |
| P-02698 | 41% | S06 | ME-01 | improved | 71 |
| P-02599 | 40% | S14 | HY-01 | improved | 54 |
| P-02037 | 39% | S04 | GI-04 | improved | 53 |
| P-02126 | 39% | S16 | DT-01 | improved | 59 |
| P-02223 | 38% | S20 | HY-01 | improved | 49 |
| P-02235 | 38% | S14 | DT-01 | improved | 50 |