Patient P-02107

Synthetic patientMETA-24 · Day 104 · 45–54 · M · baseline S17Steering view · 3D Open companion preview

Therapy response

Stable

Tolerance

Deteriorating

GI state

Improving

Inflammatory state

Favorable

Nutritional resilience

Favorable

Discontinuation risk

13%

Trajectory

Baseline → today → 30-day prediction · hover a day for signals and events

solid = observed · dashed = predicted

Day 0 META-24 started — Baseline state S17
Day 12 Trajectory diverged from prediction — Observed response fell below the model's expected path.
Day 22 GI-04 recommended — GI Support Protocol GI-04
Day 23 Patient accepted — Started GI-04 in the companion
Day 31 No meaningful change — GI Support Protocol GI-04

What changed?

Trajectory began diverging from predicted response on Day 12.

Primary contributors, last 14 days

GI instability-6
Toxicity+6
Inflammatory activity+3
Nutritional resilience+3
Treatment adherence-2

What helped?

GI Support Protocol GI-04Day 22
Result: no meaningful change

LIFE OS recommendation

No intervention is indicated right now. The trajectory is stable relative to similar patients. See what worked for similar patients.

Daily trackers

Molecule settings

The trackers this program marks as important, last 14 days vs the 14 before.

Active minutes

Wearable

61 min

stable · +2.1 vs previous 14 d

Sleep duration

Wearable

7.2 h

stable · -0.3 vs previous 14 d

Energy level

Daily log

6.2/10

stable · +0.2 vs previous 14 d

Steps

Wearable

7,296

stable · +50 vs previous 14 d

GI burden

Companion

18.5/100

improving · -2.7 vs previous 14 d

Adherence

Companion

92.4 %

stable · +1.8 vs previous 14 d

Sleep quality

Wearable

66.7/100

worsening · -7.2 vs previous 14 d

Glucose, CGM daily mean

CGM

119 mg/dL

stable · -0.6 vs previous 14 d

This trajectory is decaying — what would help, what would not

Steering view →

Heading towards restoration · 69 from the failing basin, 29 from restoration.

Would help

No untried action with strong evidence. Compose one from primitives.
More protein
GI -7.2 next day on high-intake days · n 26

Would not help

GI-04 GI Support Protocol
already tried, no meaningful change
Keep caffeine low
GI +7.7 next day on high-intake days · n 19
Keep fat low
GI +6.9 next day on high-intake days · n 18

State influencers · digestive

Next-day GI change on high-intake vs low-intake days, last 60 days. Attribution from this patient's own log; sensitivity set by their biology.

Caffeine
+7.7detractor · 95%
Protein
-7.2supporter · 95%
Dietary fat load
+6.9detractor · 95%
Ultra-processed food
-2.5no signal · 47%
Simple carbohydrates
+2no signal · 21%
Histamine load
+1.9no signal · 28%
Insoluble fibre
-1.7no signal · 27%
Alcohol
+0.3no signal · 15%

Biological layers

Which pathways look influenced, and by which layer of this person's biology.

Pathways under pressure

Butyrate / short-chain fatty acid production ↓60
- MicrobiomeButyrate capacity 44/100
- MicrobiomeF. prausnitzii depleted
Drug metabolism and exposure ↑40
- DNACYP2D6 poor metabolizer → higher exposure
Mucosal barrier integrity ↓30
- MicrobiomeAkkermansia low → thinner mucus layer
Autonomic recovery ↓25
- WearableResting HR 73 bpm
Inflammatory signalling ↑20
- MicrobiomeBacteroides fragilis expansion

DNA

Fictional pharmacogenomic panel

CYP2D6 Poor metabolizer
Higher exposure at standard dose

Microbiome

Shannon diversity 3.1 · butyrate capacity 44/100

Akkermansia muciniphilaLow
Faecalibacterium prausnitziiLow
Bacteroides fragilisHigh
Bifidobacterium longumLow
EnterobacteriaceaeNormal

Wearable, last 14 days

daily evolution fed into the runtime

HRV: 69 ms
Sleep: 7.4 h
Steps: 7,447
Resting HR: 71 bpm

Daily log: GI score 19, nutritional resilience 67, adherence 92.

What this patient sees in NostraAI

The content that steers the trajectory: what to eat, what to do, what to take.

Open companion preview

What to eat

Keep meals regular; three to four moderate portions spaced through the day
Include a cooked vegetable portion with each main meal
Add one soluble-fibre source (oats, cooked carrots, banana) to breakfast
Eat slowly and stop at comfortable fullness — smaller volume, more often

What to do

Log the daily check-in; one line is enough
Keep the current walking rhythm
Keep the sleep window steady
Keep hydration steady: small amounts through the day rather than large volumes at once

What to take

Take the dose at the same time relative to your evening meal
No additional supplements this week
Fictional demo item: continue vitamin D as before

284 biologically similar trajectories

Black: this patient. Green: similar patients whose intervention worked. Orange: similar patients where it did not.

Patient	Similarity	Baseline	Intervention	Outcome	Response today
P-02048	31%	S02	—	—	77
P-02365	33%	S08	—	—	72
P-02698	32%	S06	ME-01	improved	71
P-02403	33%	S03	—	—	71
P-02335	34%	S04	—	—	70
P-02214	34%	S08	SC-12	no change	69
P-02356	34%	S08	—	—	69
P-02293	33%	S15	HY-01	no change	68
P-02442	33%	S14	—	—	68
P-02463	36%	S18	—	—	68
P-02518	32%	S17	DT-01	improved	68
P-02637	34%	S11	—	—	67